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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
XPNPEP1
All Species:
13.94
Human Site:
S246
Identified Species:
25.56
UniProt:
Q9NQW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQW7
NP_065116.2
623
69918
S246
G
D
R
I
D
A
P
S
V
K
E
H
L
L
L
Chimpanzee
Pan troglodytes
XP_508027
716
80518
S289
G
D
R
I
D
A
P
S
V
K
E
H
L
L
L
Rhesus Macaque
Macaca mulatta
XP_001085192
845
94680
S492
G
D
R
I
D
A
P
S
V
K
E
H
L
L
L
Dog
Lupus familis
XP_544010
623
69820
S246
G
D
R
I
D
D
P
S
V
K
E
H
L
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6P1B1
623
69573
G246
G
D
R
V
D
A
P
G
V
K
Q
H
L
L
L
Rat
Rattus norvegicus
O54975
623
69639
G246
G
D
R
I
D
A
P
G
V
K
Q
H
L
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512739
650
72831
D273
G
D
R
V
K
A
P
D
V
R
E
H
L
L
L
Chicken
Gallus gallus
XP_421751
623
69997
A246
G
D
R
M
M
D
P
A
V
R
E
H
L
Q
L
Frog
Xenopus laevis
NP_001084745
621
69004
G244
G
E
R
V
A
D
P
G
F
R
E
H
L
L
L
Zebra Danio
Brachydanio rerio
NP_998145
620
69412
A246
S
K
R
L
S
D
P
A
I
R
E
H
L
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477409
613
68487
F247
S
G
K
L
P
T
D
F
V
Q
H
Q
K
E
N
Honey Bee
Apis mellifera
XP_394094
623
70424
A252
I
N
K
L
T
E
E
A
R
Q
Q
L
I
I
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07825
749
84906
S375
N
P
F
N
D
D
I
S
E
Y
F
K
I
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87
70.7
98.2
N.A.
95.8
95.6
N.A.
83.3
80.5
74.4
73.5
N.A.
47.9
48.4
N.A.
N.A.
Protein Similarity:
100
87
70.7
99
N.A.
98.5
98
N.A.
90.6
90.8
87.3
86
N.A.
66.6
67
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
80
86.6
N.A.
73.3
60
53.3
40
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
86.6
80
73.3
66.6
N.A.
26.6
53.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
47
0
24
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
62
0
0
54
39
8
8
0
0
0
0
0
0
0
% D
% Glu:
0
8
0
0
0
8
8
0
8
0
62
0
0
16
8
% E
% Phe:
0
0
8
0
0
0
0
8
8
0
8
0
0
0
8
% F
% Gly:
70
8
0
0
0
0
0
24
0
0
0
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
77
0
0
0
% H
% Ile:
8
0
0
39
0
0
8
0
8
0
0
0
16
8
0
% I
% Lys:
0
8
16
0
8
0
0
0
0
47
0
8
8
0
0
% K
% Leu:
0
0
0
24
0
0
0
0
0
0
0
8
77
62
70
% L
% Met:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
8
0
0
0
0
0
0
0
0
0
8
8
% N
% Pro:
0
8
0
0
8
0
77
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
24
8
0
8
0
% Q
% Arg:
0
0
77
0
0
0
0
0
8
31
0
0
0
0
0
% R
% Ser:
16
0
0
0
8
0
0
39
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
24
0
0
0
0
70
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _