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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: XPNPEP1 All Species: 37.58
Human Site: Y527 Identified Species: 68.89
UniProt: Q9NQW7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQW7 NP_065116.2 623 69918 Y527 V T D E P G Y Y E D G A F G I
Chimpanzee Pan troglodytes XP_508027 716 80518 Y620 V T D E P G Y Y E D G A F G I
Rhesus Macaque Macaca mulatta XP_001085192 845 94680 F754 G Y Y E D G A F G I R I E N V
Dog Lupus familis XP_544010 623 69820 Y527 V T D E P G Y Y E D G A F G I
Cat Felis silvestris
Mouse Mus musculus Q6P1B1 623 69573 Y527 V T D E P G Y Y E D G A F G I
Rat Rattus norvegicus O54975 623 69639 Y527 V T D E P G Y Y E D G A F G I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512739 650 72831 Y554 V T D E P G Y Y E D G S F G I
Chicken Gallus gallus XP_421751 623 69997 Y527 V S D E P G Y Y E D G S F G I
Frog Xenopus laevis NP_001084745 621 69004 Y525 L S D E P G Y Y E D G S F G I
Zebra Danio Brachydanio rerio NP_998145 620 69412 Y527 V S D E P G Y Y E D G S F G I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477409 613 68487 F520 F I S N E P G F Y Q D G E F G
Honey Bee Apis mellifera XP_394094 623 70424 Y528 F L S N E P G Y Y E D E K F G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q07825 749 84906 Y663 I I S N E P G Y Y K D G E Y G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 87 70.7 98.2 N.A. 95.8 95.6 N.A. 83.3 80.5 74.4 73.5 N.A. 47.9 48.4 N.A. N.A.
Protein Similarity: 100 87 70.7 99 N.A. 98.5 98 N.A. 90.6 90.8 87.3 86 N.A. 66.6 67 N.A. N.A.
P-Site Identity: 100 100 13.3 100 N.A. 100 100 N.A. 93.3 86.6 80 86.6 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 100 26.6 100 N.A. 100 100 N.A. 100 100 100 100 N.A. 6.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 36.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 52.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 0 0 39 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 70 0 8 0 0 0 0 70 24 0 0 0 0 % D
% Glu: 0 0 0 77 24 0 0 0 70 8 0 8 24 0 0 % E
% Phe: 16 0 0 0 0 0 0 16 0 0 0 0 70 16 0 % F
% Gly: 8 0 0 0 0 77 24 0 8 0 70 16 0 70 24 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 16 0 0 0 0 0 0 0 8 0 8 0 0 70 % I
% Lys: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 0 % K
% Leu: 8 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 24 0 0 0 0 0 0 0 0 0 8 0 % N
% Pro: 0 0 0 0 70 24 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % R
% Ser: 0 24 24 0 0 0 0 0 0 0 0 31 0 0 0 % S
% Thr: 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 62 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 0 0 0 70 85 24 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _