KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRDM6
All Species:
4.55
Human Site:
Y176
Identified Species:
12.5
UniProt:
Q9NQX0
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQX0
NP_001129711.1
595
64452
Y176
S
A
E
E
L
D
Y
Y
L
Y
G
Q
Q
R
M
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082029
571
64054
P152
G
P
D
T
L
I
P
P
P
L
V
D
A
S
L
Dog
Lupus familis
XP_544117
571
64407
K151
C
G
P
E
I
L
I
K
P
T
A
V
N
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q3UZD5
596
64484
Y177
S
A
E
E
L
D
Y
Y
L
Y
G
Q
Q
R
M
Rat
Rattus norvegicus
P0C6Y7
796
92561
R186
N
V
E
V
N
R
Y
R
L
R
E
R
K
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507530
809
89789
P225
G
A
F
T
L
N
P
P
N
R
I
K
Q
K
L
Chicken
Gallus gallus
XP_424413
503
55787
P119
D
N
R
N
G
E
C
P
M
H
G
P
L
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007458
366
40835
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794184
678
75009
G184
Y
P
G
C
A
M
S
G
L
P
S
H
R
T
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
24.8
26.7
N.A.
95.1
20.2
N.A.
30.1
71.2
N.A.
24.3
N.A.
N.A.
N.A.
N.A.
25.3
Protein Similarity:
100
N.A.
40.5
39.5
N.A.
96.8
31.4
N.A.
39.9
73.7
N.A.
36.2
N.A.
N.A.
N.A.
N.A.
37.7
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
100
20
N.A.
20
6.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
20
13.3
N.A.
100
46.6
N.A.
46.6
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
0
12
0
0
0
0
0
12
0
12
12
0
% A
% Cys:
12
0
0
12
0
0
12
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
0
0
23
0
0
0
0
0
12
0
12
12
% D
% Glu:
0
0
34
34
0
12
0
0
0
0
12
0
0
0
0
% E
% Phe:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
23
12
12
0
12
0
0
12
0
0
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
12
0
12
0
12
0
% H
% Ile:
0
0
0
0
12
12
12
0
0
0
12
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
12
12
12
0
% K
% Leu:
0
0
0
0
45
12
0
0
45
12
0
0
12
0
34
% L
% Met:
0
0
0
0
0
12
0
0
12
0
0
0
0
0
23
% M
% Asn:
12
12
0
12
12
12
0
0
12
0
0
0
12
0
0
% N
% Pro:
0
23
12
0
0
0
23
34
23
12
0
12
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
23
34
0
0
% Q
% Arg:
0
0
12
0
0
12
0
12
0
23
0
12
12
23
0
% R
% Ser:
23
0
0
0
0
0
12
0
0
0
12
0
0
12
23
% S
% Thr:
0
0
0
23
0
0
0
0
0
12
0
0
0
12
0
% T
% Val:
0
12
0
12
0
0
0
0
0
0
12
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
34
23
0
23
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _