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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO5C All Species: 16.97
Human Site: S347 Identified Species: 33.94
UniProt: Q9NQX4 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQX4 NP_061198 1742 202810 S347 A V G N E R S S V S E D D S H
Chimpanzee Pan troglodytes XP_510411 1843 214146 S448 A V G N E R S S V S E D D S H
Rhesus Macaque Macaca mulatta XP_001084476 1835 212895 T349 S R D A D S C T I P P K H E P
Dog Lupus familis XP_544680 1811 210003 S416 A V G N E R S S V S E D D R H
Cat Felis silvestris
Mouse Mus musculus Q99104 1853 215577 T349 S R D S D S C T I P P K H E P
Rat Rattus norvegicus Q9QYF3 1828 211745 T349 S R D S D S C T I P P K H E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q02440 1829 212364 A349 S R D S D S C A I P P K H D P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691143 1746 201863 F348 A K D P E K S F I G S R D P H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3Z6 2167 250290 T342 V V D N L D A T E I P E H I N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91443 2098 239766 V341 T N D N M E S V D V A D P S T
Sea Urchin Strong. purpuratus NP_999655 1824 211646 K348 P D Q H E S C K I E V E S E S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 S357 K K T R N D A S L S A D E P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 50.7 89.5 N.A. 50.8 51.5 N.A. N.A. 52.5 N.A. 64.5 N.A. 27 N.A. 23.7 44.9
Protein Similarity: 100 94.1 70 92.9 N.A. 69.6 70 N.A. N.A. 70.6 N.A. 80.8 N.A. 44.3 N.A. 40.3 62.5
P-Site Identity: 100 100 0 93.3 N.A. 0 0 N.A. N.A. 0 N.A. 33.3 N.A. 13.3 N.A. 26.6 6.6
P-Site Similarity: 100 100 26.6 93.3 N.A. 33.3 33.3 N.A. N.A. 33.3 N.A. 46.6 N.A. 40 N.A. 26.6 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 0 9 0 0 17 9 0 0 17 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 42 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 59 0 34 17 0 0 9 0 0 42 34 9 0 % D
% Glu: 0 0 0 0 42 9 0 0 9 9 25 17 9 34 0 % E
% Phe: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 0 25 0 0 0 0 0 0 9 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 42 0 34 % H
% Ile: 0 0 0 0 0 0 0 0 50 9 0 0 0 9 0 % I
% Lys: 9 17 0 0 0 9 0 9 0 0 0 34 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 0 42 9 0 0 0 0 0 0 0 0 0 17 % N
% Pro: 9 0 0 9 0 0 0 0 0 34 42 0 9 17 34 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 34 0 9 0 25 0 0 0 0 0 9 0 9 0 % R
% Ser: 34 0 0 25 0 42 42 34 0 34 9 0 9 25 9 % S
% Thr: 9 0 9 0 0 0 0 34 0 0 0 0 0 0 9 % T
% Val: 9 34 0 0 0 0 0 9 25 9 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _