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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO5C
All Species:
6.06
Human Site:
S353
Identified Species:
12.12
UniProt:
Q9NQX4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQX4
NP_061198
1742
202810
S353
S
S
V
S
E
D
D
S
H
L
K
V
F
C
E
Chimpanzee
Pan troglodytes
XP_510411
1843
214146
S454
S
S
V
S
E
D
D
S
H
L
K
V
F
C
E
Rhesus Macaque
Macaca mulatta
XP_001084476
1835
212895
E355
C
T
I
P
P
K
H
E
P
L
C
I
F
C
D
Dog
Lupus familis
XP_544680
1811
210003
R422
S
S
V
S
E
D
D
R
H
L
E
V
F
C
E
Cat
Felis silvestris
Mouse
Mus musculus
Q99104
1853
215577
E355
C
T
I
P
P
K
H
E
P
L
T
I
F
C
D
Rat
Rattus norvegicus
Q9QYF3
1828
211745
E355
C
T
I
P
P
K
H
E
P
L
I
I
F
C
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q02440
1829
212364
D355
C
A
I
P
P
K
H
D
P
L
T
I
F
C
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691143
1746
201863
P354
S
F
I
G
S
R
D
P
H
L
A
I
F
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3Z6
2167
250290
I348
A
T
E
I
P
E
H
I
N
V
E
R
V
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P91443
2098
239766
S347
S
V
D
V
A
D
P
S
T
L
V
R
I
A
K
Sea Urchin
Strong. purpuratus
NP_999655
1824
211646
E354
C
K
I
E
V
E
S
E
S
L
P
I
L
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P19524
1574
180662
P363
A
S
L
S
A
D
E
P
N
L
K
L
A
C
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.9
50.7
89.5
N.A.
50.8
51.5
N.A.
N.A.
52.5
N.A.
64.5
N.A.
27
N.A.
23.7
44.9
Protein Similarity:
100
94.1
70
92.9
N.A.
69.6
70
N.A.
N.A.
70.6
N.A.
80.8
N.A.
44.3
N.A.
40.3
62.5
P-Site Identity:
100
100
20
86.6
N.A.
20
20
N.A.
N.A.
20
N.A.
40
N.A.
0
N.A.
26.6
13.3
P-Site Similarity:
100
100
46.6
93.3
N.A.
46.6
46.6
N.A.
N.A.
46.6
N.A.
60
N.A.
40
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
32.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
51.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
17
0
0
0
0
0
9
0
9
17
0
% A
% Cys:
42
0
0
0
0
0
0
0
0
0
9
0
0
84
0
% C
% Asp:
0
0
9
0
0
42
34
9
0
0
0
0
0
0
42
% D
% Glu:
0
0
9
9
25
17
9
34
0
0
17
0
0
0
34
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
67
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
0
42
0
34
0
0
0
0
0
0
% H
% Ile:
0
0
50
9
0
0
0
9
0
0
9
50
9
0
0
% I
% Lys:
0
9
0
0
0
34
0
0
0
0
25
0
0
0
9
% K
% Leu:
0
0
9
0
0
0
0
0
0
92
0
9
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% N
% Pro:
0
0
0
34
42
0
9
17
34
0
9
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
9
0
0
0
17
0
0
0
% R
% Ser:
42
34
0
34
9
0
9
25
9
0
0
0
0
0
9
% S
% Thr:
0
34
0
0
0
0
0
0
9
0
17
0
0
0
0
% T
% Val:
0
9
25
9
9
0
0
0
0
9
9
25
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _