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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MYO5C All Species: 12.12
Human Site: Y633 Identified Species: 24.24
UniProt: Q9NQX4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQX4 NP_061198 1742 202810 Y633 S K F R S S L Y L L M E T L N
Chimpanzee Pan troglodytes XP_510411 1843 214146 Y734 S K F R S S L Y L L M E T L N
Rhesus Macaque Macaca mulatta XP_001084476 1835 212895 V635 A K E H K K T V G H Q F R N S
Dog Lupus familis XP_544680 1811 210003 Y702 S K F R G S L Y L L M E T L N
Cat Felis silvestris
Mouse Mus musculus Q99104 1853 215577 V635 A K E H K K T V G H Q F R N S
Rat Rattus norvegicus Q9QYF3 1828 211745 V635 A K E H K K T V G L Q F R N S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q02440 1829 212364 T635 T S K E H K K T V G H Q F R N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691143 1746 201863 L633 F R S S L Y L L M E T L N A T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3Z6 2167 250290 D613 T Q F R K S L D A L M K T L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P91443 2098 239766 E610 N Q F R R S L E Q L M S Q L T
Sea Urchin Strong. purpuratus NP_999655 1824 211646 Y633 Q F R D S L T Y L M M K L N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P19524 1574 180662 I652 S M F K Q S L I E L M N T I N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.9 50.7 89.5 N.A. 50.8 51.5 N.A. N.A. 52.5 N.A. 64.5 N.A. 27 N.A. 23.7 44.9
Protein Similarity: 100 94.1 70 92.9 N.A. 69.6 70 N.A. N.A. 70.6 N.A. 80.8 N.A. 44.3 N.A. 40.3 62.5
P-Site Identity: 100 100 6.6 93.3 N.A. 6.6 13.3 N.A. N.A. 6.6 N.A. 6.6 N.A. 53.3 N.A. 46.6 26.6
P-Site Similarity: 100 100 20 93.3 N.A. 20 26.6 N.A. N.A. 26.6 N.A. 20 N.A. 80 N.A. 60 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 32.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 51.9 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 0 0 0 0 0 9 0 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 25 9 0 0 0 9 9 9 0 25 0 0 0 % E
% Phe: 9 9 50 0 0 0 0 0 0 0 0 25 9 0 0 % F
% Gly: 0 0 0 0 9 0 0 0 25 9 0 0 0 0 0 % G
% His: 0 0 0 25 9 0 0 0 0 17 9 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % I
% Lys: 0 50 9 9 34 34 9 0 0 0 0 17 0 0 0 % K
% Leu: 0 0 0 0 9 9 59 9 34 59 0 9 9 42 0 % L
% Met: 0 9 0 0 0 0 0 0 9 9 59 0 0 0 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 0 0 9 9 34 42 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 9 17 0 0 9 0 0 0 9 0 25 9 9 0 0 % Q
% Arg: 0 9 9 42 9 0 0 0 0 0 0 0 25 9 0 % R
% Ser: 34 9 9 9 25 50 0 0 0 0 0 9 0 0 42 % S
% Thr: 17 0 0 0 0 0 34 9 0 0 9 0 42 0 17 % T
% Val: 0 0 0 0 0 0 0 25 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 34 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _