KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NPDC1
All Species:
4.55
Human Site:
S111
Identified Species:
12.5
UniProt:
Q9NQX5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQX5
NP_056207.3
325
34516
S111
Q
E
L
A
R
K
E
S
G
H
S
T
P
P
L
Chimpanzee
Pan troglodytes
XP_520386
227
23583
H36
L
R
G
A
A
A
G
H
P
D
V
A
A
C
P
Rhesus Macaque
Macaca mulatta
XP_001091499
326
34479
S113
Q
E
L
A
R
K
E
S
G
H
S
T
P
P
L
Dog
Lupus familis
XP_537787
267
28233
F70
C
G
P
C
L
Q
P
F
Q
E
D
P
Q
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64322
332
35786
R117
E
K
E
A
G
H
S
R
L
T
A
Q
P
L
L
Rat
Rattus norvegicus
NP_001004231
331
35498
R117
E
K
E
A
G
H
P
R
L
T
A
Q
P
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233959
305
33035
G108
R
S
H
A
L
R
D
G
K
P
R
T
T
L
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001122255
307
33666
K115
K
Q
Q
L
S
E
S
K
H
S
D
S
A
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_726489
850
93210
P531
E
D
Y
E
E
Y
A
P
I
E
P
T
T
E
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.3
84.3
64.3
N.A.
77.1
76.7
N.A.
N.A.
46.4
N.A.
41.5
N.A.
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
68.6
86.5
68.3
N.A.
83.4
84.5
N.A.
N.A.
57.5
N.A.
54.4
N.A.
27.4
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
100
6.6
N.A.
20
13.3
N.A.
N.A.
13.3
N.A.
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
100
13.3
N.A.
40
33.3
N.A.
N.A.
33.3
N.A.
33.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
67
12
12
12
0
0
0
23
12
23
0
12
% A
% Cys:
12
0
0
12
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
12
0
0
0
0
12
0
0
12
23
0
0
0
0
% D
% Glu:
34
23
23
12
12
12
23
0
0
23
0
0
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
12
12
0
23
0
12
12
23
0
0
0
0
12
0
% G
% His:
0
0
12
0
0
23
0
12
12
23
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
12
23
0
0
0
23
0
12
12
0
0
0
0
0
0
% K
% Leu:
12
0
23
12
23
0
0
0
23
0
0
0
0
34
45
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
0
0
23
12
12
12
12
12
45
34
23
% P
% Gln:
23
12
12
0
0
12
0
0
12
0
0
23
12
0
12
% Q
% Arg:
12
12
0
0
23
12
0
23
0
0
12
0
0
0
0
% R
% Ser:
0
12
0
0
12
0
23
23
0
12
23
12
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
23
0
45
23
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _