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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD7
All Species:
17.27
Human Site:
S238
Identified Species:
34.55
UniProt:
Q9NQZ7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQZ7
NP_065087.1
604
68960
S238
R
F
D
H
E
D
E
S
D
A
E
A
T
Q
E
Chimpanzee
Pan troglodytes
XP_507974
604
68938
S238
R
F
D
H
E
D
E
S
D
A
E
A
T
Q
E
Rhesus Macaque
Macaca mulatta
XP_001106407
604
68949
S238
R
F
D
H
E
D
E
S
D
A
E
A
T
Q
E
Dog
Lupus familis
XP_850381
604
68939
S238
R
F
D
H
E
D
E
S
D
A
E
A
P
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCT4
606
68956
S238
R
F
D
H
E
D
E
S
D
S
D
T
S
V
D
Rat
Rattus norvegicus
P97687
511
57389
G175
I
I
T
G
Q
E
E
G
A
Y
G
W
I
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
N267
D
E
A
V
V
E
V
N
I
P
G
G
E
D
K
Chicken
Gallus gallus
P79784
495
54515
G159
G
G
A
K
I
L
S
G
E
E
E
G
V
F
G
Frog
Xenopus laevis
NP_001088548
616
70594
N251
D
D
A
V
V
E
V
N
V
P
G
A
D
N
K
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
Q251
H
D
A
V
V
E
V
Q
V
P
G
S
D
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
M212
A
R
Q
K
T
V
G
M
I
D
M
G
G
A
S
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
L201
I
P
L
E
Y
G
F
L
F
P
E
K
N
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
96.6
N.A.
92
25.1
N.A.
60.3
25.8
60.2
58.7
N.A.
N.A.
N.A.
32.9
50
Protein Similarity:
100
99.6
99.6
98
N.A.
96
43.7
N.A.
72.5
42
73.2
71.1
N.A.
N.A.
N.A.
52.1
63
P-Site Identity:
100
100
100
93.3
N.A.
60
6.6
N.A.
0
6.6
6.6
6.6
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
20
N.A.
20
13.3
26.6
26.6
N.A.
N.A.
N.A.
0
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
34
0
0
0
0
0
9
34
0
42
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
17
42
0
0
42
0
0
42
9
9
0
17
9
9
% D
% Glu:
0
9
0
9
42
34
50
0
9
9
50
0
9
0
42
% E
% Phe:
0
42
0
0
0
0
9
0
9
0
0
0
0
9
0
% F
% Gly:
9
9
0
9
0
9
9
17
0
0
34
25
9
0
9
% G
% His:
9
0
0
42
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
9
0
0
9
0
0
0
17
0
0
0
9
0
9
% I
% Lys:
0
0
0
17
0
0
0
0
0
0
0
9
0
0
17
% K
% Leu:
0
0
9
0
0
9
0
9
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
17
0
0
0
0
9
9
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
34
0
0
9
0
0
% P
% Gln:
0
0
9
0
9
0
0
9
0
0
0
0
0
42
9
% Q
% Arg:
42
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
9
42
0
9
0
9
9
0
9
% S
% Thr:
0
0
9
0
9
0
0
0
0
0
0
9
25
9
0
% T
% Val:
0
0
0
25
25
9
25
0
17
0
0
0
9
17
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
9
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _