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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD7
All Species:
18.79
Human Site:
S381
Identified Species:
37.58
UniProt:
Q9NQZ7
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQZ7
NP_065087.1
604
68960
S381
R
G
R
G
D
W
V
S
C
G
A
M
L
S
P
Chimpanzee
Pan troglodytes
XP_507974
604
68938
S381
R
G
R
G
D
W
V
S
C
G
A
M
L
S
P
Rhesus Macaque
Macaca mulatta
XP_001106407
604
68949
S381
R
G
R
G
D
W
V
S
C
G
A
M
L
S
P
Dog
Lupus familis
XP_850381
604
68939
S381
R
G
K
G
D
W
A
S
C
G
A
M
L
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCT4
606
68956
S381
R
G
K
G
D
W
A
S
C
R
T
L
L
S
P
Rat
Rattus norvegicus
P97687
511
57389
K307
C
T
K
R
F
E
K
K
L
P
F
N
Q
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
L410
R
G
T
G
D
F
T
L
C
R
E
T
I
Q
P
Chicken
Gallus gallus
P79784
495
54515
R291
S
P
C
T
E
K
E
R
P
G
L
P
L
N
T
Frog
Xenopus laevis
NP_001088548
616
70594
L394
R
G
T
G
D
F
Q
L
C
R
Q
I
I
Q
P
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
R386
R
G
S
G
D
F
E
R
C
R
L
L
L
Q
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
Y345
K
A
E
A
A
K
C
Y
F
G
A
V
P
A
P
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
G333
A
A
R
S
R
Y
E
G
L
L
I
N
S
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
96.6
N.A.
92
25.1
N.A.
60.3
25.8
60.2
58.7
N.A.
N.A.
N.A.
32.9
50
Protein Similarity:
100
99.6
99.6
98
N.A.
96
43.7
N.A.
72.5
42
73.2
71.1
N.A.
N.A.
N.A.
52.1
63
P-Site Identity:
100
100
100
86.6
N.A.
66.6
0
N.A.
40
13.3
40
46.6
N.A.
N.A.
N.A.
20
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
6.6
N.A.
53.3
26.6
60
60
N.A.
N.A.
N.A.
40
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
9
9
0
17
0
0
0
42
0
0
9
0
% A
% Cys:
9
0
9
0
0
0
9
0
67
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
67
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
9
9
25
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
9
25
0
0
9
0
9
0
0
9
0
% F
% Gly:
0
67
0
67
0
0
0
9
0
50
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
9
17
0
0
% I
% Lys:
9
0
25
0
0
17
9
9
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
17
17
9
17
17
59
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
34
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
17
0
9
0
% N
% Pro:
0
9
0
0
0
0
0
0
9
9
0
9
9
0
75
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
9
0
9
25
9
% Q
% Arg:
67
0
34
9
9
0
0
17
0
34
0
0
0
0
0
% R
% Ser:
9
0
9
9
0
0
0
42
0
0
0
0
9
42
0
% S
% Thr:
0
9
17
9
0
0
9
0
0
0
9
9
0
9
9
% T
% Val:
0
0
0
0
0
0
25
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
42
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _