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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENTPD7 All Species: 32.42
Human Site: S466 Identified Species: 64.85
UniProt: Q9NQZ7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQZ7 NP_065087.1 604 68960 S466 F K N G L F S S H A D E H R L
Chimpanzee Pan troglodytes XP_507974 604 68938 S466 F K N G L F S S H A D E H R L
Rhesus Macaque Macaca mulatta XP_001106407 604 68949 S466 F K N G L F S S H A D E H R L
Dog Lupus familis XP_850381 604 68939 S466 F K N G L F S S H A D E H R L
Cat Felis silvestris
Mouse Mus musculus Q3TCT4 606 68956 S466 F K N G L F S S H A D E H R L
Rat Rattus norvegicus P97687 511 57389 S392 E I T K N F C S K P W E E V K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507040 633 71884 S495 F D R G L Y A S H A D L H R L
Chicken Gallus gallus P79784 495 54515 T376 D L K D A A E T I C A T S W N
Frog Xenopus laevis NP_001088548 616 70594 S479 F D R G L Y A S H A D L H R L
Zebra Danio Brachydanio rerio NP_001002419 611 69763 S471 F D R G L Y A S H A D Q H R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q21815 552 62492 S430 F K S A W I T S V L H D G F S
Sea Urchin Strong. purpuratus XP_785341 537 60729 I418 G G V Y Q A N I N F D N S E F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 99.5 96.6 N.A. 92 25.1 N.A. 60.3 25.8 60.2 58.7 N.A. N.A. N.A. 32.9 50
Protein Similarity: 100 99.6 99.6 98 N.A. 96 43.7 N.A. 72.5 42 73.2 71.1 N.A. N.A. N.A. 52.1 63
P-Site Identity: 100 100 100 100 N.A. 100 20 N.A. 66.6 0 66.6 66.6 N.A. N.A. N.A. 20 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 80 6.6 80 86.6 N.A. N.A. N.A. 40 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 17 25 0 0 67 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 9 0 0 9 0 0 0 0 0 % C
% Asp: 9 25 0 9 0 0 0 0 0 0 75 9 0 0 0 % D
% Glu: 9 0 0 0 0 0 9 0 0 0 0 50 9 9 0 % E
% Phe: 75 0 0 0 0 50 0 0 0 9 0 0 0 9 9 % F
% Gly: 9 9 0 67 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 67 0 9 0 67 0 0 % H
% Ile: 0 9 0 0 0 9 0 9 9 0 0 0 0 0 0 % I
% Lys: 0 50 9 9 0 0 0 0 9 0 0 0 0 0 9 % K
% Leu: 0 9 0 0 67 0 0 0 0 9 0 17 0 0 67 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 42 0 9 0 9 0 9 0 0 9 0 0 9 % N
% Pro: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % P
% Gln: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % Q
% Arg: 0 0 25 0 0 0 0 0 0 0 0 0 0 67 0 % R
% Ser: 0 0 9 0 0 0 42 84 0 0 0 0 17 0 9 % S
% Thr: 0 0 9 0 0 0 9 9 0 0 0 9 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 9 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 9 0 0 9 0 % W
% Tyr: 0 0 0 9 0 25 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _