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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD7
All Species:
18.48
Human Site:
T580
Identified Species:
36.97
UniProt:
Q9NQZ7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQZ7
NP_065087.1
604
68960
T580
R
R
I
H
H
R
Q
T
R
A
S
A
P
L
D
Chimpanzee
Pan troglodytes
XP_507974
604
68938
T580
R
R
I
H
H
R
Q
T
R
A
S
A
P
L
D
Rhesus Macaque
Macaca mulatta
XP_001106407
604
68949
T580
R
R
I
H
H
R
Q
T
R
A
S
A
P
L
D
Dog
Lupus familis
XP_850381
604
68939
T580
R
R
I
H
H
R
Q
T
R
T
S
A
P
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCT4
606
68956
T582
H
R
I
H
R
R
Q
T
R
A
S
A
P
L
D
Rat
Rattus norvegicus
P97687
511
57389
S501
I
T
G
L
F
I
F
S
K
P
S
Y
F
W
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
L609
R
R
I
H
R
R
M
L
R
N
G
S
S
A
S
Chicken
Gallus gallus
P79784
495
54515
Y485
T
A
L
L
T
A
V
Y
L
L
R
R
S
K
S
Frog
Xenopus laevis
NP_001088548
616
70594
Q593
R
R
I
H
R
R
M
Q
R
N
T
S
S
S
A
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
M586
R
R
I
H
N
R
S
M
L
H
R
S
A
S
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
N541
S
Y
K
M
L
K
E
N
R
T
S
S
S
F
L
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
I527
V
Q
W
T
L
G
A
I
L
Y
R
T
R
F
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
96.6
N.A.
92
25.1
N.A.
60.3
25.8
60.2
58.7
N.A.
N.A.
N.A.
32.9
50
Protein Similarity:
100
99.6
99.6
98
N.A.
96
43.7
N.A.
72.5
42
73.2
71.1
N.A.
N.A.
N.A.
52.1
63
P-Site Identity:
100
100
100
93.3
N.A.
86.6
6.6
N.A.
40
0
40
33.3
N.A.
N.A.
N.A.
13.3
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
20
N.A.
46.6
6.6
53.3
46.6
N.A.
N.A.
N.A.
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
9
0
0
34
0
42
9
9
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
42
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
9
0
9
0
0
0
0
0
9
17
0
% F
% Gly:
0
0
9
0
0
9
0
0
0
0
9
0
0
0
0
% G
% His:
9
0
0
67
34
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
9
0
67
0
0
9
0
9
0
0
0
0
0
0
0
% I
% Lys:
0
0
9
0
0
9
0
0
9
0
0
0
0
9
9
% K
% Leu:
0
0
9
17
17
0
0
9
25
9
0
0
0
42
17
% L
% Met:
0
0
0
9
0
0
17
9
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
17
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
0
42
0
0
% P
% Gln:
0
9
0
0
0
0
42
9
0
0
0
0
0
0
0
% Q
% Arg:
59
67
0
0
25
67
0
0
67
0
25
9
9
0
0
% R
% Ser:
9
0
0
0
0
0
9
9
0
0
59
34
34
17
17
% S
% Thr:
9
9
0
9
9
0
0
42
0
17
9
9
0
0
0
% T
% Val:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
9
0
0
0
0
0
9
0
9
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _