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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ENTPD7
All Species:
26.67
Human Site:
Y435
Identified Species:
53.33
UniProt:
Q9NQZ7
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQZ7
NP_065087.1
604
68960
Y435
V
L
R
I
G
G
R
Y
H
G
P
T
F
A
K
Chimpanzee
Pan troglodytes
XP_507974
604
68938
Y435
V
L
R
I
G
G
R
Y
H
G
P
T
F
A
K
Rhesus Macaque
Macaca mulatta
XP_001106407
604
68949
Y435
V
L
R
I
G
G
R
Y
H
G
P
T
F
A
K
Dog
Lupus familis
XP_850381
604
68939
Y435
V
L
R
I
G
G
R
Y
H
G
P
T
F
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3TCT4
606
68956
Y435
V
L
R
I
G
G
H
Y
H
G
P
T
F
A
K
Rat
Rattus norvegicus
P97687
511
57389
A361
G
S
F
G
A
F
S
A
F
Y
F
V
M
D
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507040
633
71884
Y464
V
L
R
M
G
G
D
Y
S
A
A
K
F
I
K
Chicken
Gallus gallus
P79784
495
54515
A345
E
V
S
G
N
F
I
A
F
S
A
F
F
Y
T
Frog
Xenopus laevis
NP_001088548
616
70594
Y448
V
L
R
M
G
G
S
Y
N
S
T
R
F
L
L
Zebra Danio
Brachydanio rerio
NP_001002419
611
69763
Y440
V
L
R
M
G
G
D
Y
N
S
T
K
Y
T
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21815
552
62492
S399
Q
Y
C
S
K
R
W
S
T
I
Q
A
E
S
K
Sea Urchin
Strong. purpuratus
XP_785341
537
60729
V387
F
K
G
T
G
D
Y
V
A
C
K
E
V
M
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.5
96.6
N.A.
92
25.1
N.A.
60.3
25.8
60.2
58.7
N.A.
N.A.
N.A.
32.9
50
Protein Similarity:
100
99.6
99.6
98
N.A.
96
43.7
N.A.
72.5
42
73.2
71.1
N.A.
N.A.
N.A.
52.1
63
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
53.3
6.6
46.6
40
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
0
N.A.
60
13.3
60
60
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
17
9
9
17
9
0
42
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
17
0
0
0
0
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% E
% Phe:
9
0
9
0
0
17
0
0
17
0
9
9
67
0
9
% F
% Gly:
9
0
9
17
75
67
0
0
0
42
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
42
0
0
0
0
0
0
% H
% Ile:
0
0
0
42
0
0
9
0
0
9
0
0
0
9
0
% I
% Lys:
0
9
0
0
9
0
0
0
0
0
9
17
0
0
59
% K
% Leu:
0
67
0
0
0
0
0
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
25
0
0
0
0
0
0
0
0
9
9
0
% M
% Asn:
0
0
0
0
9
0
0
0
17
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
42
0
0
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
67
0
0
9
34
0
0
0
0
9
0
0
0
% R
% Ser:
0
9
9
9
0
0
17
9
9
25
0
0
0
9
0
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
17
42
0
9
9
% T
% Val:
67
9
0
0
0
0
0
9
0
0
0
9
9
0
9
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
9
67
0
9
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _