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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACSS2 All Species: 21.82
Human Site: T628 Identified Species: 60
UniProt: Q9NR19 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR19 NP_061147.1 701 78580 T628 H T F S P K L T E E L K K Q I
Chimpanzee Pan troglodytes XP_001161837 701 78563 T628 H T F S P K L T E E L K K Q I
Rhesus Macaque Macaca mulatta XP_001103176 701 78502 T628 H T F S P K L T E E L K K Q I
Dog Lupus familis XP_534395 657 74578 T584 Y T F S P T L T E E L K K Q I
Cat Felis silvestris
Mouse Mus musculus Q9QXG4 701 78903 T628 H T F S P T L T E E L K K Q I
Rat Rattus norvegicus NP_001101263 701 78869 T628 H T F S P T L T E E L K K Q I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417342 640 71465 A567 H D F T K N L A D E L K K Q V
Frog Xenopus laevis NP_001085453 680 76399 A607 I K Y T E R I A E E V K K Q V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VP61 670 75941 I597 E V F D Q K L I S D L K K M V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.7 87 N.A. 92.8 93.7 N.A. N.A. 71.3 69.1 N.A. N.A. 60.4 N.A. N.A. N.A.
Protein Similarity: 100 99.5 99.4 91 N.A. 96 96.8 N.A. N.A. 81.5 80.4 N.A. N.A. 75.6 N.A. N.A. N.A.
P-Site Identity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 53.3 33.3 N.A. N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 73.3 73.3 N.A. N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 23 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 12 0 12 0 0 0 0 12 12 0 0 0 0 0 % D
% Glu: 12 0 0 0 12 0 0 0 78 89 0 0 0 0 0 % E
% Phe: 0 0 89 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 12 0 0 0 0 0 12 12 0 0 0 0 0 0 67 % I
% Lys: 0 12 0 0 12 45 0 0 0 0 0 100 100 0 0 % K
% Leu: 0 0 0 0 0 0 89 0 0 0 89 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 12 0 % M
% Asn: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 67 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 12 0 0 0 0 0 0 0 0 89 0 % Q
% Arg: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 67 0 0 0 0 12 0 0 0 0 0 0 % S
% Thr: 0 67 0 23 0 34 0 67 0 0 0 0 0 0 0 % T
% Val: 0 12 0 0 0 0 0 0 0 0 12 0 0 0 34 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 12 0 12 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _