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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACSS2
All Species:
24.85
Human Site:
Y218
Identified Species:
68.33
UniProt:
Q9NR19
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR19
NP_061147.1
701
78580
Y218
L
I
T
T
D
A
F
Y
R
G
E
K
L
V
N
Chimpanzee
Pan troglodytes
XP_001161837
701
78563
Y218
L
I
T
T
D
A
F
Y
R
G
E
K
L
V
N
Rhesus Macaque
Macaca mulatta
XP_001103176
701
78502
Y218
L
I
T
T
D
A
F
Y
R
G
E
K
L
V
N
Dog
Lupus familis
XP_534395
657
74578
Y218
L
I
T
T
D
A
F
Y
R
G
E
K
L
V
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9QXG4
701
78903
Y218
L
I
T
T
D
A
F
Y
R
G
E
K
L
V
N
Rat
Rattus norvegicus
NP_001101263
701
78869
Y218
L
I
T
T
D
A
F
Y
R
G
E
K
L
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417342
640
71465
S206
A
D
G
A
C
S
Q
S
P
P
L
K
R
L
C
Frog
Xenopus laevis
NP_001085453
680
76399
F209
L
I
T
A
D
G
V
F
R
G
E
K
P
I
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP61
670
75941
S223
K
V
E
E
M
G
H
S
V
E
K
C
I
V
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.7
87
N.A.
92.8
93.7
N.A.
N.A.
71.3
69.1
N.A.
N.A.
60.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.4
91
N.A.
96
96.8
N.A.
N.A.
81.5
80.4
N.A.
N.A.
75.6
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
60
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
20
73.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
23
0
67
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
12
0
0
12
% C
% Asp:
0
12
0
0
78
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
12
12
0
0
0
0
0
12
78
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
67
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
0
0
23
0
0
0
78
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% H
% Ile:
0
78
0
0
0
0
0
0
0
0
0
0
12
12
0
% I
% Lys:
12
0
0
0
0
0
0
0
0
0
12
89
0
0
0
% K
% Leu:
78
0
0
0
0
0
0
0
0
0
12
0
67
12
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
78
% N
% Pro:
0
0
0
0
0
0
0
0
12
12
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
78
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
0
12
0
23
0
0
0
0
0
0
0
% S
% Thr:
0
0
78
67
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
12
0
12
0
0
0
0
78
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _