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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT8
All Species:
9.7
Human Site:
S31
Identified Species:
17.78
UniProt:
Q9NR22
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR22
NP_062828.3
394
45291
S31
T
E
V
N
S
P
P
S
Q
P
P
Q
P
V
V
Chimpanzee
Pan troglodytes
XP_001156280
394
45300
S31
T
E
V
N
S
P
P
S
Q
P
P
Q
P
V
V
Rhesus Macaque
Macaca mulatta
XP_001113609
466
52877
K32
N
A
E
D
M
T
S
K
D
Y
Y
F
D
S
Y
Dog
Lupus familis
XP_543867
379
43518
C30
V
P
T
K
P
V
Q
C
V
H
H
V
S
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAK3
394
45258
P31
T
E
V
S
S
A
P
P
Q
P
P
Q
P
V
I
Rat
Rattus norvegicus
Q63009
353
40504
S20
V
S
C
G
Q
A
E
S
S
E
K
P
N
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521175
437
49423
S71
I
Q
V
S
N
G
P
S
Q
P
A
P
P
A
Q
Chicken
Gallus gallus
XP_423669
369
42416
R33
L
Q
P
G
C
P
G
R
G
K
M
A
K
F
L
Frog
Xenopus laevis
Q6VRB0
351
40419
G18
V
S
C
A
L
P
E
G
S
V
K
P
N
A
E
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
S46
S
I
S
S
I
P
S
S
Q
S
L
Q
P
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH48
530
59709
M89
A
D
T
D
A
A
Q
M
G
R
R
S
Y
A
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
D31
R
F
E
D
A
D
E
D
E
V
A
E
G
S
G
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
K15
D
S
A
T
E
K
T
K
L
S
E
S
E
Q
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
59.2
94.6
N.A.
98.4
71.8
N.A.
79.4
88
72
79.4
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
100
68
95.4
N.A.
99.2
81.2
N.A.
84.6
91.1
81.9
86.6
N.A.
43.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
73.3
6.6
N.A.
40
6.6
6.6
33.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
0
N.A.
86.6
6.6
N.A.
60
20
6.6
46.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.4
42.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.7
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
16
24
0
0
0
0
16
8
0
31
0
% A
% Cys:
0
0
16
0
8
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
24
0
8
0
8
8
0
0
0
8
0
0
% D
% Glu:
0
24
16
0
8
0
24
0
8
8
8
8
8
0
16
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
8
0
8
0
% F
% Gly:
0
0
0
16
0
8
8
8
16
0
0
0
8
0
8
% G
% His:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
8
% H
% Ile:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
0
8
0
16
0
8
16
0
8
0
0
% K
% Leu:
8
0
0
0
8
0
0
0
8
0
8
0
0
0
8
% L
% Met:
0
0
0
0
8
0
0
8
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
16
8
0
0
0
0
0
0
0
16
0
0
% N
% Pro:
0
8
8
0
8
39
31
8
0
31
24
24
39
0
8
% P
% Gln:
0
16
0
0
8
0
16
0
39
0
0
31
0
8
16
% Q
% Arg:
8
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% R
% Ser:
8
24
8
24
24
0
16
39
16
16
0
16
8
24
0
% S
% Thr:
24
0
16
8
0
8
8
0
0
0
0
0
0
8
0
% T
% Val:
24
0
31
0
0
8
0
0
8
16
0
8
0
24
24
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
8
0
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _