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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT8
All Species:
28.48
Human Site:
Y231
Identified Species:
52.22
UniProt:
Q9NR22
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR22
NP_062828.3
394
45291
Y231
V
A
I
E
D
R
Q
Y
K
D
F
K
I
H
W
Chimpanzee
Pan troglodytes
XP_001156280
394
45300
Y231
V
A
I
E
D
R
Q
Y
K
D
F
K
I
H
W
Rhesus Macaque
Macaca mulatta
XP_001113609
466
52877
Y300
H
W
K
Q
T
V
F
Y
M
E
D
Y
L
T
V
Dog
Lupus familis
XP_543867
379
43518
Y216
V
A
I
E
D
R
Q
Y
K
D
F
K
I
H
W
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAK3
394
45258
Y231
V
A
I
E
D
R
Q
Y
K
D
F
K
I
H
W
Rat
Rattus norvegicus
Q63009
353
40504
W198
K
D
Y
K
I
H
W
W
E
N
V
Y
G
F
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521175
437
49423
Y274
T
A
I
E
D
R
Q
Y
K
D
F
K
I
H
W
Chicken
Gallus gallus
XP_423669
369
42416
W213
Y
K
D
F
K
I
H
W
W
E
N
V
Y
G
F
Frog
Xenopus laevis
Q6VRB0
351
40419
W196
K
D
Y
K
I
H
W
W
E
N
V
Y
G
F
D
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
Y256
V
A
I
E
D
R
Q
Y
K
D
F
K
I
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH48
530
59709
Y302
E
S
L
Y
S
E
Q
Y
N
K
A
N
F
W
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
Y227
T
A
I
E
D
S
E
Y
K
E
D
K
I
E
F
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
D193
W
Q
D
V
Y
G
F
D
Y
S
P
F
V
P
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
59.2
94.6
N.A.
98.4
71.8
N.A.
79.4
88
72
79.4
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
100
68
95.4
N.A.
99.2
81.2
N.A.
84.6
91.1
81.9
86.6
N.A.
43.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
100
N.A.
100
0
N.A.
93.3
0
0
100
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
100
N.A.
100
26.6
N.A.
93.3
20
26.6
100
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.4
42.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.7
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
53.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
54
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
16
16
0
54
0
0
8
0
47
16
0
0
0
16
% D
% Glu:
8
0
0
54
0
8
8
0
16
24
0
0
0
8
0
% E
% Phe:
0
0
0
8
0
0
16
0
0
0
47
8
8
16
16
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
16
8
0
% G
% His:
8
0
0
0
0
16
8
0
0
0
0
0
0
47
0
% H
% Ile:
0
0
54
0
16
8
0
0
0
0
0
0
54
0
0
% I
% Lys:
16
8
8
16
8
0
0
0
54
8
0
54
0
0
0
% K
% Leu:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
8
16
8
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% P
% Gln:
0
8
0
8
0
0
54
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
47
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
8
0
0
0
8
0
0
0
0
0
% S
% Thr:
16
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% T
% Val:
39
0
0
8
0
8
0
0
0
0
16
8
8
0
8
% V
% Trp:
8
8
0
0
0
0
16
24
8
0
0
0
0
8
47
% W
% Tyr:
8
0
16
8
8
0
0
70
8
0
0
24
8
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _