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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRMT8
All Species:
23.33
Human Site:
Y76
Identified Species:
42.78
UniProt:
Q9NR22
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR22
NP_062828.3
394
45291
Y76
E
M
T
S
R
D
Y
Y
F
D
S
Y
A
H
F
Chimpanzee
Pan troglodytes
XP_001156280
394
45300
Y76
E
M
T
S
R
D
Y
Y
F
D
S
Y
A
H
F
Rhesus Macaque
Macaca mulatta
XP_001113609
466
52877
M86
S
G
T
G
I
L
C
M
F
A
A
K
A
G
A
Dog
Lupus familis
XP_543867
379
43518
H71
S
Y
A
H
F
G
I
H
E
E
M
L
K
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PAK3
394
45258
Y76
E
M
T
S
R
D
Y
Y
F
D
S
Y
A
H
F
Rat
Rattus norvegicus
Q63009
353
40504
S61
R
T
L
T
Y
R
N
S
M
F
H
N
R
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521175
437
49423
Y119
E
M
T
S
R
D
Y
Y
F
D
S
Y
A
H
F
Chicken
Gallus gallus
XP_423669
369
42416
R75
E
V
R
T
L
T
Y
R
N
S
M
Y
H
N
K
Frog
Xenopus laevis
Q6VRB0
351
40419
S59
R
T
L
T
Y
R
N
S
M
F
H
N
R
H
L
Zebra Danio
Brachydanio rerio
Q5RGQ2
419
48204
Y101
E
M
T
S
R
D
Y
Y
F
D
S
Y
A
H
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VH48
530
59709
E137
S
V
F
S
Q
R
T
E
E
S
S
A
S
Q
Y
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SU94
390
43875
Y72
D
T
T
S
A
D
Y
Y
F
D
S
Y
S
H
F
Baker's Yeast
Sacchar. cerevisiae
P38074
348
39768
L56
A
I
I
Q
N
K
D
L
F
K
D
K
I
V
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
59.2
94.6
N.A.
98.4
71.8
N.A.
79.4
88
72
79.4
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
100
68
95.4
N.A.
99.2
81.2
N.A.
84.6
91.1
81.9
86.6
N.A.
43.9
N.A.
N.A.
N.A.
P-Site Identity:
100
100
20
0
N.A.
100
6.6
N.A.
100
20
6.6
100
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
13.3
N.A.
100
13.3
N.A.
100
40
13.3
100
N.A.
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
49.4
42.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
67.7
61.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
86.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
8
0
0
0
0
8
8
8
47
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
47
8
0
0
47
8
0
0
8
0
% D
% Glu:
47
0
0
0
0
0
0
8
16
8
0
0
0
0
8
% E
% Phe:
0
0
8
0
8
0
0
0
62
16
0
0
0
0
47
% F
% Gly:
0
8
0
8
0
8
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
8
0
0
0
8
0
0
16
0
8
62
0
% H
% Ile:
0
8
8
0
8
0
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
8
0
16
8
0
8
% K
% Leu:
0
0
16
0
8
8
0
8
0
0
0
8
0
0
24
% L
% Met:
0
39
0
0
0
0
0
8
16
0
16
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
16
0
8
0
0
16
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
16
0
8
0
39
24
0
8
0
0
0
0
16
0
0
% R
% Ser:
24
0
0
54
0
0
0
16
0
16
54
0
16
0
0
% S
% Thr:
0
24
54
24
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
16
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
16
0
54
47
0
0
0
54
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _