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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GDF3
All Species:
16.97
Human Site:
S246
Identified Species:
33.94
UniProt:
Q9NR23
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR23
NP_065685.1
364
41387
S246
N
P
D
Q
C
H
P
S
R
K
R
R
A
A
I
Chimpanzee
Pan troglodytes
XP_508988
364
41318
S246
N
P
D
Q
C
H
S
S
R
K
R
R
A
A
I
Rhesus Macaque
Macaca mulatta
XP_001112644
364
41302
S246
N
P
D
E
C
P
P
S
R
K
R
R
A
A
I
Dog
Lupus familis
XP_534896
365
41219
S246
N
P
E
Q
C
H
P
S
S
R
K
R
R
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q07104
366
41509
S247
N
P
K
H
C
H
P
S
S
R
K
R
R
A
A
Rat
Rattus norvegicus
P49001
393
44364
S255
H
Q
D
E
H
S
W
S
Q
V
R
P
L
L
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509474
383
41376
V264
H
P
Q
Q
C
R
P
V
A
R
R
R
R
A
V
Chicken
Gallus gallus
Q90751
353
40328
K238
H
P
L
H
K
R
E
K
R
Q
A
K
H
K
Q
Frog
Xenopus laevis
Q9YGV1
354
40298
Q236
D
P
S
N
C
K
T
Q
R
A
K
R
S
T
H
Zebra Danio
Brachydanio rerio
P35621
355
40183
R237
N
P
L
Q
C
R
S
R
R
K
R
S
A
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07713
588
65849
E316
V
K
S
I
P
A
D
E
K
L
K
A
A
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P48970
395
43818
R266
E
Y
R
Q
C
S
K
R
N
R
R
N
K
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.4
80.2
N.A.
69.4
29.2
N.A.
43.5
30.2
42.3
42
N.A.
22.1
N.A.
N.A.
30.6
Protein Similarity:
100
99.4
98
87.4
N.A.
79.7
47
N.A.
58.7
49.7
59.6
60.7
N.A.
37.9
N.A.
N.A.
48.3
P-Site Identity:
100
93.3
86.6
53.3
N.A.
53.3
20
N.A.
46.6
13.3
26.6
53.3
N.A.
6.6
N.A.
N.A.
20
P-Site Similarity:
100
93.3
93.3
73.3
N.A.
66.6
46.6
N.A.
66.6
33.3
46.6
60
N.A.
26.6
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
9
0
0
9
9
9
9
42
42
17
% A
% Cys:
0
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
34
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
9
17
0
0
9
9
0
0
0
0
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
25
0
0
17
9
34
0
0
0
0
0
0
9
0
9
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
25
% I
% Lys:
0
9
9
0
9
9
9
9
9
34
34
9
9
9
0
% K
% Leu:
0
0
17
0
0
0
0
0
0
9
0
0
9
9
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
50
0
0
9
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
75
0
0
9
9
42
0
0
0
0
9
0
0
0
% P
% Gln:
0
9
9
50
0
0
0
9
9
9
0
0
0
0
17
% Q
% Arg:
0
0
9
0
0
25
0
17
50
34
59
59
25
9
0
% R
% Ser:
0
0
17
0
0
17
17
50
17
0
0
9
9
9
0
% S
% Thr:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% T
% Val:
9
0
0
0
0
0
0
9
0
9
0
0
0
0
17
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _