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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DDX21
All Species:
26.67
Human Site:
S281
Identified Species:
45.13
UniProt:
Q9NR30
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR30
NP_004719.2
783
87344
S281
N
Q
V
S
K
D
F
S
D
I
T
K
K
L
S
Chimpanzee
Pan troglodytes
XP_507825
783
87227
S281
N
Q
V
S
K
D
F
S
D
I
T
K
K
L
S
Rhesus Macaque
Macaca mulatta
XP_001110939
783
87067
S281
N
Q
V
S
K
D
F
S
D
I
T
K
K
L
S
Dog
Lupus familis
XP_851746
784
87489
S282
N
Q
V
S
R
D
F
S
D
I
T
R
K
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIK5
851
93564
S353
N
Q
V
S
K
D
F
S
D
I
T
K
K
L
S
Rat
Rattus norvegicus
Q3B8Q1
782
85947
S277
N
Q
V
S
K
D
F
S
D
I
T
K
K
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519340
757
84164
S267
I
Q
V
G
R
D
F
S
D
I
T
K
K
L
T
Chicken
Gallus gallus
XP_001232052
713
79167
I252
Y
N
G
Q
I
D
L
I
R
S
G
I
D
I
L
Frog
Xenopus laevis
NP_001082033
800
89347
R316
I
Q
I
T
N
E
L
R
S
M
T
K
K
L
K
Zebra Danio
Brachydanio rerio
NP_001120807
759
84566
K261
I
Q
V
T
K
D
F
K
D
I
T
R
K
L
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786504
657
72975
A196
Q
I
S
E
Y
F
E
A
I
G
P
H
L
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39189
671
72872
G210
L
S
S
C
C
L
Y
G
G
D
S
Y
P
V
Q
Baker's Yeast
Sacchar. cerevisiae
P24784
617
67899
F156
V
P
E
P
I
L
D
F
S
S
P
P
L
D
E
Red Bread Mold
Neurospora crassa
Q9P6U9
688
72037
I227
V
Q
K
Y
S
I
P
I
V
M
G
G
R
D
L
Conservation
Percent
Protein Identity:
100
99.8
97.6
87.2
N.A.
76.1
84.9
N.A.
66.4
62.2
51.7
62.2
N.A.
N.A.
N.A.
N.A.
45.5
Protein Similarity:
100
99.8
98.8
91.5
N.A.
82.4
90.2
N.A.
78.4
75.8
69.6
75.6
N.A.
N.A.
N.A.
N.A.
60.5
P-Site Identity:
100
100
100
80
N.A.
100
100
N.A.
73.3
6.6
33.3
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
13.3
60
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
38
23.8
26.4
Protein Similarity:
N.A.
N.A.
N.A.
53.3
40.2
39.8
P-Site Identity:
N.A.
N.A.
N.A.
0
0
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
65
8
0
58
8
0
0
8
15
0
% D
% Glu:
0
0
8
8
0
8
8
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
0
0
0
8
58
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
8
0
0
0
8
8
8
15
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
22
8
8
0
15
8
0
15
8
58
0
8
0
8
0
% I
% Lys:
0
0
8
0
43
0
0
8
0
0
0
50
65
0
8
% K
% Leu:
8
0
0
0
0
15
15
0
0
0
0
0
15
65
15
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
0
0
0
% M
% Asn:
43
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
0
8
0
0
0
15
8
8
0
0
% P
% Gln:
8
72
0
8
0
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
15
0
0
8
8
0
0
15
8
0
0
% R
% Ser:
0
8
15
43
8
0
0
50
15
15
8
0
0
8
43
% S
% Thr:
0
0
0
15
0
0
0
0
0
0
65
0
0
0
15
% T
% Val:
15
0
58
0
0
0
0
0
8
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
8
0
8
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _