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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DDX21 All Species: 20
Human Site: S74 Identified Species: 33.85
UniProt: Q9NR30 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.31
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR30 NP_004719.2 783 87344 S74 V D M N S P K S K K A K K K E
Chimpanzee Pan troglodytes XP_507825 783 87227 S74 V D M N S P K S K K A K K K E
Rhesus Macaque Macaca mulatta XP_001110939 783 87067 S74 V D M N S P K S K K A K K K D
Dog Lupus familis XP_851746 784 87489 S74 V D M N S P K S K K A K K K E
Cat Felis silvestris
Mouse Mus musculus Q9JIK5 851 93564 R74 D V D P P K S R K A K K Q E E
Rat Rattus norvegicus Q3B8Q1 782 85947 K74 D V G P P K S K K A K K Q E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519340 757 84164 S82 D A L S P P K S K K A K K K E
Chicken Gallus gallus XP_001232052 713 79167 K70 E E E C S S P K L K K A K T G
Frog Xenopus laevis NP_001082033 800 89347 K106 K K K L K E G K E D S D A Q E
Zebra Danio Brachydanio rerio NP_001120807 759 84566 L74 G N T D T H T L K V K K K K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786504 657 72975 R14 V S L N G E I R K K K K S K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q39189 671 72872 S28 L D T P E L D S K K G K K E Q
Baker's Yeast Sacchar. cerevisiae P24784 617 67899
Red Bread Mold Neurospora crassa Q9P6U9 688 72037 D45 H L R G K M G D A A P P M A G
Conservation
Percent
Protein Identity: 100 99.8 97.6 87.2 N.A. 76.1 84.9 N.A. 66.4 62.2 51.7 62.2 N.A. N.A. N.A. N.A. 45.5
Protein Similarity: 100 99.8 98.8 91.5 N.A. 82.4 90.2 N.A. 78.4 75.8 69.6 75.6 N.A. N.A. N.A. N.A. 60.5
P-Site Identity: 100 100 93.3 100 N.A. 20 20 N.A. 66.6 20 6.6 26.6 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 33.3 33.3 N.A. 80 26.6 26.6 46.6 N.A. N.A. N.A. N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 38 23.8 26.4
Protein Similarity: N.A. N.A. N.A. 53.3 40.2 39.8
P-Site Identity: N.A. N.A. N.A. 40 0 0
P-Site Similarity: N.A. N.A. N.A. 60 0 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 0 0 8 22 36 8 8 8 0 % A
% Cys: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 22 36 8 8 0 0 8 8 0 8 0 8 0 0 8 % D
% Glu: 8 8 8 0 8 15 0 0 8 0 0 0 0 22 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 8 8 8 0 15 0 0 0 8 0 0 0 15 % G
% His: 8 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 8 % I
% Lys: 8 8 8 0 15 15 36 22 72 58 36 72 58 50 8 % K
% Leu: 8 8 15 8 0 8 0 8 8 0 0 0 0 0 0 % L
% Met: 0 0 29 0 0 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 0 36 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 22 22 36 8 0 0 0 8 8 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 15 8 8 % Q
% Arg: 0 0 8 0 0 0 0 15 0 0 0 0 0 0 0 % R
% Ser: 0 8 0 8 36 8 15 43 0 0 8 0 8 0 0 % S
% Thr: 0 0 15 0 8 0 8 0 0 0 0 0 0 8 0 % T
% Val: 36 15 0 0 0 0 0 0 0 8 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _