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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SAR1A All Species: 13.64
Human Site: S106 Identified Species: 20
UniProt: Q9NR31 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR31 NP_001136120.1 198 22367 S106 L V D C A D H S R L V E S K V
Chimpanzee Pan troglodytes XP_001151106 190 21329 L99 A M N G I I F L V D C A D H S
Rhesus Macaque Macaca mulatta XP_001109673 198 22416 S106 L V D C A D H S R L V E S K V
Dog Lupus familis XP_538630 198 22404 E106 L V D C A D H E R L L E S K E
Cat Felis silvestris
Mouse Mus musculus P36536 198 22352 S106 L V D C A D H S R L M E S K V
Rat Rattus norvegicus Q5HZY2 198 22391 E106 L V D C A D H E R L L E S K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506794 198 22407 P106 L V D C A D H P R L Q E S K V
Chicken Gallus gallus XP_421589 198 22372 S106 L V D C A D H S R L M E S K V
Frog Xenopus laevis NP_001087684 198 22372 G106 L V D C L D H G R L M E S K V
Zebra Danio Brachydanio rerio NP_001019548 198 22210 G106 L V D C I D H G R L A E S K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_732717 193 21793 R102 I D A W D R G R F Q E S K N E
Honey Bee Apis mellifera XP_393115 193 21812 R102 V D A S D R S R L P E S K A E
Nematode Worm Caenorhab. elegans Q23445 193 21690 E102 L I D V A D A E R M Q E S R V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q01474 193 21968 R102 V D A Y D K E R F A E S K R E
Baker's Yeast Sacchar. cerevisiae P20606 190 21432 D99 N G I V F L V D A A D P E R F
Red Bread Mold Neurospora crassa P0C583 189 21564 K98 I V F L V D A K D H E R L P E
Conservation
Percent
Protein Identity: 100 79.8 93.9 90.9 N.A. 98.4 90.4 N.A. 96.4 97.4 93.4 91.9 N.A. 69.6 70.7 63.1 N.A.
Protein Similarity: 100 86.3 96.4 97.9 N.A. 98.9 97.9 N.A. 97.9 98.9 96.4 95.4 N.A. 82.3 83.8 81.3 N.A.
P-Site Identity: 100 0 100 80 N.A. 93.3 80 N.A. 86.6 93.3 80 73.3 N.A. 0 0 53.3 N.A.
P-Site Similarity: 100 13.3 100 86.6 N.A. 100 86.6 N.A. 86.6 100 86.6 73.3 N.A. 6.6 6.6 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 59.6 59 60.1
Protein Similarity: N.A. N.A. N.A. 75.2 70.2 77.2
P-Site Identity: N.A. N.A. N.A. 0 0 13.3
P-Site Similarity: N.A. N.A. N.A. 13.3 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 19 0 50 0 13 0 7 13 7 7 0 7 0 % A
% Cys: 0 0 0 57 0 0 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 19 63 0 19 69 0 7 7 7 7 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 7 19 0 0 25 63 7 0 38 % E
% Phe: 0 0 7 0 7 0 7 0 13 0 0 0 0 0 7 % F
% Gly: 0 7 0 7 0 0 7 13 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 57 0 0 7 0 0 0 7 0 % H
% Ile: 13 7 7 0 13 7 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 7 0 7 0 0 0 0 19 57 0 % K
% Leu: 63 0 0 7 7 7 0 7 7 57 13 0 7 0 0 % L
% Met: 0 7 0 0 0 0 0 0 0 7 19 0 0 0 0 % M
% Asn: 7 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 7 0 7 0 7 0 7 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 13 0 0 0 0 % Q
% Arg: 0 0 0 0 0 13 0 19 63 0 0 7 0 19 0 % R
% Ser: 0 0 0 7 0 0 7 25 0 0 0 19 63 0 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 13 63 0 13 7 0 7 0 7 0 13 0 0 0 44 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _