KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLE4
All Species:
15.45
Human Site:
S25
Identified Species:
28.33
UniProt:
Q9NR33
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR33
NP_063949.2
117
12209
S25
P
A
G
E
A
A
A
S
Q
P
Q
A
P
T
S
Chimpanzee
Pan troglodytes
XP_001162584
155
16644
S24
P
A
G
E
A
A
V
S
Q
P
Q
A
P
T
S
Rhesus Macaque
Macaca mulatta
XP_001111739
117
12216
L25
P
A
G
E
A
A
A
L
Q
P
Q
A
P
T
S
Dog
Lupus familis
XP_540212
257
26663
P165
P
S
G
E
A
A
A
P
Q
P
Q
A
P
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQ36
118
12221
S25
P
G
G
E
A
A
A
S
Q
A
Q
A
P
T
S
Rat
Rattus norvegicus
NP_001102104
118
12250
S25
P
G
G
E
A
A
A
S
Q
A
Q
A
P
T
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514772
97
10201
G21
M
E
G
V
N
G
D
G
A
T
I
P
Q
P
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090193
116
12354
S24
Q
E
D
A
G
P
S
S
P
P
A
A
H
P
A
Zebra Danio
Brachydanio rerio
XP_001918535
179
19518
G35
P
E
E
D
A
G
S
G
Q
T
G
P
T
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611669
155
17352
T62
Q
L
T
E
K
P
V
T
N
G
N
K
A
P
A
Honey Bee
Apis mellifera
XP_001121637
102
11783
V24
E
K
Q
K
E
K
L
V
K
L
P
L
G
R
I
Nematode Worm
Caenorhab. elegans
NP_497087
179
20668
V28
V
R
E
I
E
E
H
V
E
E
L
V
R
S
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FGP7
202
21991
Y39
S
N
P
Q
L
R
N
Y
W
I
E
Q
M
E
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.1
99.1
44.3
N.A.
94.9
94
N.A.
64.9
N.A.
60.6
43.5
N.A.
34.1
35.9
20.1
N.A.
Protein Similarity:
100
74.1
99.1
44.7
N.A.
94.9
94.9
N.A.
67.5
N.A.
76.9
50.8
N.A.
54.8
59.8
31.2
N.A.
P-Site Identity:
100
93.3
93.3
86.6
N.A.
86.6
80
N.A.
6.6
N.A.
20
20
N.A.
6.6
0
0
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
86.6
86.6
N.A.
6.6
N.A.
33.3
33.3
N.A.
20
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
24
0
8
54
47
39
0
8
16
8
54
8
8
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
8
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
24
16
54
16
8
0
0
8
8
8
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
16
54
0
8
16
0
16
0
8
8
0
8
0
8
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
8
8
0
0
0
8
% I
% Lys:
0
8
0
8
8
8
0
0
8
0
0
8
0
0
0
% K
% Leu:
0
8
0
0
8
0
8
8
0
8
8
8
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
8
0
8
0
8
0
8
0
0
0
8
% N
% Pro:
54
0
8
0
0
16
0
8
8
39
8
16
47
24
0
% P
% Gln:
16
0
8
8
0
0
0
0
54
0
47
8
8
0
16
% Q
% Arg:
0
8
0
0
0
8
0
0
0
0
0
0
8
8
0
% R
% Ser:
8
8
0
0
0
0
16
39
0
0
0
0
0
8
39
% S
% Thr:
0
0
8
0
0
0
0
8
0
16
0
0
8
47
8
% T
% Val:
8
0
0
8
0
0
16
16
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _