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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAN1C1 All Species: 40.61
Human Site: S403 Identified Species: 74.44
UniProt: Q9NR34 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR34 NP_065112.1 630 70911 S403 L I K S W L M S G K T D M E A
Chimpanzee Pan troglodytes XP_518868 1022 112702 S795 L L K A W L M S D K T D L E A
Rhesus Macaque Macaca mulatta XP_001113249 641 72899 S412 L L K A W L M S D K T D H E A
Dog Lupus familis XP_535351 597 66972 S372 L I K S W L M S A K T D V E A
Cat Felis silvestris
Mouse Mus musculus P45700 655 73257 S428 L L K A W L M S D K T D L E A
Rat Rattus norvegicus NP_001102157 625 70650 S398 L I K S W L M S A K T D M E A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510614 483 55360 K266 K T D E E A K K M Y F E A V Q
Chicken Gallus gallus XP_417735 727 81565 S501 L I K S W L M S D K K D S E A
Frog Xenopus laevis NP_001086502 643 72831 S414 L L K A W L L S D R T D L E A
Zebra Danio Brachydanio rerio XP_694435 618 69847 S391 L L K A W L M S D K I D E E G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P53624 667 74947 S433 L L K A W L Q S G Q T D E E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q18788 590 66931 S372 L I K S Y V Q S N Y T D T Q A
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32906 549 63039 S332 Q G L H G Q L S P K M D H L V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 37.7 50.2 83.9 N.A. 50.9 88.7 N.A. 49 56.9 49.1 53.8 N.A. 43.7 N.A. 40.9 N.A.
Protein Similarity: 100 47.9 67.7 87.6 N.A. 66.8 93.3 N.A. 63.1 67.5 66.4 69.5 N.A. 63.1 N.A. 59.5 N.A.
P-Site Identity: 100 73.3 73.3 86.6 N.A. 73.3 93.3 N.A. 0 80 60 60 N.A. 66.6 N.A. 53.3 N.A.
P-Site Similarity: 100 93.3 86.6 93.3 N.A. 93.3 93.3 N.A. 6.6 80 93.3 73.3 N.A. 86.6 N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 36.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 47 0 8 0 0 16 0 0 0 8 0 77 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 8 0 0 0 0 0 47 0 0 93 0 0 0 % D
% Glu: 0 0 0 8 8 0 0 0 0 0 0 8 16 77 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 0 0 16 0 0 0 0 0 8 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 16 0 0 % H
% Ile: 0 39 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 85 0 0 0 8 8 0 70 8 0 0 0 0 % K
% Leu: 85 47 8 0 0 77 16 0 0 0 0 0 24 8 0 % L
% Met: 0 0 0 0 0 0 62 0 8 0 8 0 16 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % P
% Gln: 8 0 0 0 0 8 16 0 0 8 0 0 0 8 8 % Q
% Arg: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 0 0 0 39 0 0 0 93 0 0 0 0 8 0 0 % S
% Thr: 0 8 0 0 0 0 0 0 0 0 70 0 8 0 0 % T
% Val: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 8 % V
% Trp: 0 0 0 0 77 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 16 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _