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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NANS
All Species:
32.42
Human Site:
Y188
Identified Species:
64.85
UniProt:
Q9NR45
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR45
NP_061819.2
359
40308
Y188
F
L
Q
C
T
S
A
Y
P
L
Q
P
E
D
V
Chimpanzee
Pan troglodytes
XP_001157766
320
35890
K149
Y
L
E
K
T
A
K
K
G
R
P
M
V
I
S
Rhesus Macaque
Macaca mulatta
XP_001113519
274
30677
F108
Y
A
E
E
V
G
I
F
F
T
A
S
G
M
D
Dog
Lupus familis
XP_538746
359
40228
Y188
F
L
Q
C
T
S
A
Y
P
L
L
P
E
D
V
Cat
Felis silvestris
Mouse
Mus musculus
NP_444409
359
40006
Y188
F
L
Q
C
T
S
A
Y
P
L
Q
P
E
D
A
Rat
Rattus norvegicus
NP_001100125
359
40033
Y188
F
L
Q
C
T
S
A
Y
P
L
Q
P
E
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506765
359
40209
Y188
I
L
Q
C
T
S
A
Y
P
L
P
P
E
D
V
Chicken
Gallus gallus
NP_001007976
359
40126
Y188
F
L
Q
C
T
S
A
Y
P
L
Q
P
E
D
V
Frog
Xenopus laevis
NP_001087593
359
40302
Y188
F
L
Q
C
T
S
A
Y
P
L
L
P
E
D
V
Zebra Danio
Brachydanio rerio
NP_996660
359
40126
Y188
I
L
Q
C
T
S
A
Y
P
L
E
P
E
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650195
372
41200
Y185
L
M
H
C
V
S
S
Y
P
T
D
P
K
D
C
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783181
296
33461
F130
D
S
I
N
V
P
F
F
K
V
G
S
G
D
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.5
75.7
95.8
N.A.
94.7
94.9
N.A.
88.3
86.9
77.4
78.8
N.A.
47.5
N.A.
N.A.
59.3
Protein Similarity:
100
85.7
76
98.8
N.A.
97.7
97.4
N.A.
94.9
94.1
90.8
92.1
N.A.
65.3
N.A.
N.A.
71.5
P-Site Identity:
100
13.3
0
93.3
N.A.
93.3
93.3
N.A.
86.6
100
93.3
86.6
N.A.
40
N.A.
N.A.
6.6
P-Site Similarity:
100
33.3
20
93.3
N.A.
93.3
93.3
N.A.
86.6
100
93.3
93.3
N.A.
60
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
9
67
0
0
0
9
0
0
0
17
% A
% Cys:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
0
0
0
0
0
0
0
0
9
0
0
84
9
% D
% Glu:
0
0
17
9
0
0
0
0
0
0
9
0
67
0
0
% E
% Phe:
50
0
0
0
0
0
9
17
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
9
0
0
9
0
9
0
17
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
9
0
0
0
9
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
9
0
0
9
9
9
0
0
0
9
0
0
% K
% Leu:
9
75
0
0
0
0
0
0
0
67
17
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
9
0
9
0
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
9
0
0
75
0
17
75
0
0
0
% P
% Gln:
0
0
67
0
0
0
0
0
0
0
34
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
9
0
0
0
75
9
0
0
0
0
17
0
0
9
% S
% Thr:
0
0
0
0
75
0
0
0
0
17
0
0
0
0
9
% T
% Val:
0
0
0
0
25
0
0
0
0
9
0
0
9
0
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _