KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3GLB2
All Species:
24.85
Human Site:
S205
Identified Species:
68.33
UniProt:
Q9NR46
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR46
NP_064530.1
395
43974
S205
R
N
Y
I
L
S
A
S
A
S
A
L
W
N
D
Chimpanzee
Pan troglodytes
XP_520303
400
44342
S205
R
N
Y
I
L
S
A
S
A
S
A
L
W
N
D
Rhesus Macaque
Macaca mulatta
XP_001109686
394
43900
S208
R
E
S
L
E
H
G
S
A
G
T
I
W
A
E
Dog
Lupus familis
XP_548427
394
43947
S205
R
N
Y
I
L
S
A
S
A
S
A
L
W
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8R3V5
400
44485
S205
R
N
Y
I
L
S
A
S
A
S
A
L
W
N
D
Rat
Rattus norvegicus
Q5PPJ9
404
44834
S209
R
N
Y
I
L
S
A
S
A
S
A
L
W
N
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508524
364
40538
E184
L
K
K
A
K
A
A
E
A
R
A
S
S
E
Q
Chicken
Gallus gallus
Q5ZJ81
403
44870
S205
R
N
Y
V
L
S
A
S
A
S
A
L
W
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035087
381
43129
F192
K
A
A
A
V
P
D
F
Q
E
T
R
P
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
62.5
96.9
N.A.
95.5
93.8
N.A.
61
82.3
N.A.
73.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
79.2
98.2
N.A.
97.7
96
N.A.
75.4
90.3
N.A.
84
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
26.6
100
N.A.
100
100
N.A.
20
86.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
46.6
100
N.A.
100
100
N.A.
26.6
100
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
12
12
23
0
12
78
0
89
0
78
0
0
12
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
67
% D
% Glu:
0
12
0
0
12
0
0
12
0
12
0
0
0
12
12
% E
% Phe:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
56
0
0
0
0
0
0
0
12
0
0
0
% I
% Lys:
12
12
12
0
12
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
12
0
0
12
67
0
0
0
0
0
0
67
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
67
0
0
0
0
0
0
0
0
0
0
0
56
12
% N
% Pro:
0
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
12
% Q
% Arg:
78
0
0
0
0
0
0
0
0
12
0
12
0
12
0
% R
% Ser:
0
0
12
0
0
67
0
78
0
67
0
12
12
12
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% T
% Val:
0
0
0
12
12
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% W
% Tyr:
0
0
67
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _