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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASH1L
All Species:
5.45
Human Site:
T1758
Identified Species:
12
UniProt:
Q9NR48
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR48
NP_060959.2
2969
332790
T1758
R
S
H
S
K
D
R
T
L
G
K
P
D
S
L
Chimpanzee
Pan troglodytes
XP_513861
2964
332149
T1758
R
S
H
S
K
D
R
T
L
G
K
P
D
S
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851926
2974
332800
A1760
H
S
H
S
K
E
R
A
L
G
K
P
D
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99MY8
2958
331289
R1754
G
H
S
Y
S
K
E
R
A
L
G
K
S
D
S
Rat
Rattus norvegicus
NP_001101159
2918
326454
R1754
G
H
S
Y
S
K
E
R
T
L
G
K
S
D
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511389
1395
154154
R358
P
K
L
A
A
K
R
R
W
T
C
S
K
P
K
Chicken
Gallus gallus
XP_422858
2954
330578
G1747
R
N
H
S
R
E
R
G
L
G
K
Q
D
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692254
2962
327377
S1726
Q
P
A
C
C
L
D
S
P
P
S
H
L
S
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW15
2226
246247
K1189
I
D
A
E
A
E
A
K
R
L
D
S
I
P
T
Honey Bee
Apis mellifera
XP_001122948
2180
246181
Q1143
L
E
K
F
T
S
N
Q
R
V
T
E
L
N
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784903
3312
363645
Q2098
K
R
K
T
T
K
Q
Q
A
T
P
P
P
S
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
94.1
N.A.
91.7
91.2
N.A.
21.5
79.9
N.A.
40.9
N.A.
26.1
26
N.A.
27.3
Protein Similarity:
100
99.6
N.A.
97
N.A.
95.3
94.4
N.A.
31.8
89.2
N.A.
53
N.A.
42.2
43.9
N.A.
43.3
P-Site Identity:
100
100
N.A.
80
N.A.
0
0
N.A.
6.6
66.6
N.A.
6.6
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
86.6
N.A.
0
0
N.A.
13.3
86.6
N.A.
20
N.A.
6.6
6.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
19
0
10
10
19
0
0
0
0
0
0
% A
% Cys:
0
0
0
10
10
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
19
10
0
0
0
10
0
37
19
0
% D
% Glu:
0
10
0
10
0
28
19
0
0
0
0
10
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
19
0
0
0
0
0
0
10
0
37
19
0
0
0
10
% G
% His:
10
19
37
0
0
0
0
0
0
0
0
10
0
0
10
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
10
19
0
28
37
0
10
0
0
37
19
10
0
10
% K
% Leu:
10
0
10
0
0
10
0
0
37
28
0
0
19
0
37
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
0
0
0
0
0
10
0
% N
% Pro:
10
10
0
0
0
0
0
0
10
10
10
37
10
19
0
% P
% Gln:
10
0
0
0
0
0
10
19
0
0
0
10
0
0
0
% Q
% Arg:
28
10
0
0
10
0
46
28
19
0
0
0
0
0
0
% R
% Ser:
0
28
19
37
19
10
0
10
0
0
10
19
19
55
19
% S
% Thr:
0
0
0
10
19
0
0
19
10
19
10
0
0
0
10
% T
% Val:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _