KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2B3
All Species:
38.18
Human Site:
S21
Identified Species:
64.62
UniProt:
Q9NR50
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR50
NP_065098.1
452
50240
S21
S
R
M
T
D
L
T
S
S
I
P
K
P
L
L
Chimpanzee
Pan troglodytes
XP_001152272
452
50208
S21
S
R
M
T
D
L
T
S
S
I
P
K
P
L
L
Rhesus Macaque
Macaca mulatta
XP_001094199
426
47513
S21
S
R
M
T
D
L
T
S
S
I
P
K
P
L
L
Dog
Lupus familis
XP_532603
452
50384
S21
S
R
M
T
D
L
T
S
S
I
P
T
L
L
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_780344
445
49783
S21
S
R
M
T
D
L
T
S
S
I
P
K
P
L
L
Rat
Rattus norvegicus
P70541
452
50417
S21
S
R
M
T
D
L
T
S
S
I
P
K
P
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508011
644
70516
S21
S
R
M
M
D
L
T
S
S
I
P
K
P
L
L
Chicken
Gallus gallus
NP_001026451
438
48916
S21
S
R
M
T
D
L
T
S
S
I
P
K
P
L
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_957368
453
50479
Y21
S
R
M
M
D
L
T
Y
N
T
P
K
P
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611046
455
50653
G22
T
R
L
P
E
V
L
G
D
A
P
K
C
L
L
Honey Bee
Apis mellifera
XP_395441
457
51785
R25
S
R
M
T
E
L
T
R
G
R
Y
K
C
L
L
Nematode Worm
Caenorhab. elegans
P80361
404
44760
T15
L
L
C
S
G
G
G
T
R
M
P
V
L
T
R
Sea Urchin
Strong. purpuratus
XP_797372
388
43828
R15
M
A
A
G
R
G
S
R
M
T
D
L
S
N
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09032
578
65681
T62
N
E
F
M
Q
H
S
T
R
L
P
K
A
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
92.9
89.5
N.A.
83.6
90.4
N.A.
53.1
68.1
N.A.
64.4
N.A.
35.5
35.8
28.9
37.8
Protein Similarity:
100
100
93.8
94.4
N.A.
89.1
95.3
N.A.
63
79.1
N.A.
81
N.A.
57.5
60.1
49.5
56.8
P-Site Identity:
100
100
100
86.6
N.A.
100
100
N.A.
93.3
100
N.A.
73.3
N.A.
33.3
60
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
93.3
100
N.A.
80
N.A.
60
66.6
26.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
0
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
15
0
0
% C
% Asp:
0
0
0
0
65
0
0
0
8
0
8
0
0
0
0
% D
% Glu:
0
8
0
0
15
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
8
15
8
8
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
58
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
79
0
0
0
% K
% Leu:
8
8
8
0
0
72
8
0
0
8
0
8
15
86
86
% L
% Met:
8
0
72
22
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
0
0
0
8
8
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
86
0
58
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
79
0
0
8
0
0
15
15
8
0
0
0
0
8
% R
% Ser:
72
0
0
8
0
0
15
58
58
0
0
0
8
0
0
% S
% Thr:
8
0
0
58
0
0
72
15
0
15
0
8
0
8
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _