KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DLL4
All Species:
21.21
Human Site:
S634
Identified Species:
42.42
UniProt:
Q9NR61
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR61
NP_061947.1
685
74605
S634
M
P
G
K
F
P
H
S
D
K
S
L
G
E
K
Chimpanzee
Pan troglodytes
XP_510318
685
74575
S634
M
P
G
K
F
P
H
S
D
K
S
L
G
E
K
Rhesus Macaque
Macaca mulatta
XP_001099250
685
74578
S634
M
P
G
K
F
P
H
S
D
K
S
L
G
E
K
Dog
Lupus familis
XP_849154
685
74341
S634
M
L
G
K
Y
S
H
S
D
K
S
L
G
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI71
686
74987
S635
M
P
G
K
Y
P
H
S
D
K
S
L
G
E
K
Rat
Rattus norvegicus
P97677
714
77360
V663
K
C
Q
S
Q
G
S
V
G
E
E
K
S
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515293
465
49913
V415
A
G
L
V
A
V
L
V
L
L
A
M
V
A
V
Chicken
Gallus gallus
XP_421132
798
87862
S747
Q
E
D
K
Y
Y
K
S
E
K
C
L
G
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q8UWJ4
717
79043
P666
S
E
A
T
K
C
E
P
L
D
S
D
S
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10041
833
88822
P769
K
G
A
S
G
G
G
P
G
A
A
E
G
K
R
Honey Bee
Apis mellifera
XP_393831
1119
119736
S1051
I
E
S
A
K
R
S
S
V
F
A
G
N
A
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P10079
1064
112055
F996
N
N
Y
D
F
P
S
F
G
F
T
V
V
R
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
92.6
N.A.
86.5
51.2
N.A.
48
59.9
N.A.
45.8
N.A.
35.7
29.3
N.A.
22.4
Protein Similarity:
100
99.7
99.7
95.9
N.A.
91.6
64.9
N.A.
55.1
70.4
N.A.
61.2
N.A.
48.7
39.8
N.A.
33.6
P-Site Identity:
100
100
100
80
N.A.
93.3
0
N.A.
0
46.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
100
6.6
N.A.
13.3
60
N.A.
20
N.A.
26.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
17
9
9
0
0
0
0
9
25
0
0
17
0
% A
% Cys:
0
9
0
0
0
9
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
9
9
0
0
0
0
42
9
0
9
0
0
9
% D
% Glu:
0
25
0
0
0
0
9
0
9
9
9
9
0
59
9
% E
% Phe:
0
0
0
0
34
0
0
9
0
17
0
0
0
0
0
% F
% Gly:
0
17
42
0
9
17
9
0
25
0
0
9
59
0
0
% G
% His:
0
0
0
0
0
0
42
0
0
0
0
0
0
0
0
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
50
17
0
9
0
0
50
0
9
0
9
50
% K
% Leu:
0
9
9
0
0
0
9
0
17
9
0
50
0
0
0
% L
% Met:
42
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% M
% Asn:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
34
0
0
0
42
0
17
0
0
0
0
0
0
0
% P
% Gln:
9
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
9
% R
% Ser:
9
0
9
17
0
9
25
59
0
0
50
0
17
0
9
% S
% Thr:
0
0
0
9
0
0
0
0
0
0
9
0
0
9
9
% T
% Val:
0
0
0
9
0
9
0
17
9
0
0
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
25
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _