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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL1
All Species:
10.61
Human Site:
S74
Identified Species:
23.33
UniProt:
Q9NR64
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR64
NP_065917.1
748
82680
S74
T
F
W
K
K
P
S
S
S
S
S
S
S
S
S
Chimpanzee
Pan troglodytes
XP_509677
751
83073
S74
T
F
W
K
K
P
S
S
S
S
S
S
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001097263
594
66540
C58
Y
L
K
Q
Q
Q
L
C
D
V
I
L
I
V
G
Dog
Lupus familis
XP_542606
663
73668
V72
S
S
E
L
R
S
Q
V
E
Y
V
C
V
L
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9JI74
751
82914
S77
W
K
K
P
S
S
S
S
S
S
S
S
S
S
S
Rat
Rattus norvegicus
Q8K430
640
69714
K70
H
S
V
A
H
N
S
K
R
H
Y
H
D
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505569
773
85142
K101
G
G
R
G
V
F
W
K
K
P
S
A
A
S
S
Chicken
Gallus gallus
XP_416994
747
82114
S71
F
W
K
K
S
A
S
S
A
S
S
S
A
A
T
Frog
Xenopus laevis
Q6NRH0
564
63190
L28
S
L
R
K
S
Q
T
L
C
D
V
T
L
R
V
Zebra Danio
Brachydanio rerio
Q5U374
564
62914
L28
A
L
R
K
S
N
T
L
C
D
I
T
L
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
E70
N
M
L
R
R
H
R
E
L
C
D
V
V
L
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
79
80.6
N.A.
94.9
35.9
N.A.
86.8
89.4
31.1
30.6
N.A.
37.4
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
79.2
83.2
N.A.
97.1
52
N.A.
91
92.3
45.8
44.5
N.A.
53.4
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
60
6.6
N.A.
20
40
6.6
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
13.3
N.A.
60
13.3
N.A.
33.3
73.3
26.6
20
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
10
0
0
10
0
0
10
19
19
0
% A
% Cys:
0
0
0
0
0
0
0
10
19
10
0
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
19
10
0
10
0
0
% D
% Glu:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
0
% E
% Phe:
10
19
0
0
0
10
0
0
0
0
0
0
0
0
10
% F
% Gly:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
10
0
0
0
10
10
0
0
0
10
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
19
0
10
0
0
% I
% Lys:
0
10
28
46
19
0
0
19
10
0
0
0
0
0
0
% K
% Leu:
0
28
10
10
0
0
10
19
10
0
0
10
19
19
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
10
0
19
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
10
10
19
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
28
10
19
0
10
0
10
0
0
0
0
19
0
% R
% Ser:
19
19
0
0
37
19
46
37
28
37
46
37
28
37
37
% S
% Thr:
19
0
0
0
0
0
19
0
0
0
0
19
0
0
10
% T
% Val:
0
0
10
0
10
0
0
10
0
10
19
10
19
10
28
% V
% Trp:
10
10
19
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _