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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ASAH2
All Species:
20
Human Site:
S310
Identified Species:
40
UniProt:
Q9NR71
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR71
NP_001072984.1
780
85516
S310
H
P
V
S
M
N
N
S
N
H
L
V
N
S
D
Chimpanzee
Pan troglodytes
XP_507791
780
85671
S310
H
P
V
S
M
N
N
S
N
H
L
V
N
S
D
Rhesus Macaque
Macaca mulatta
XP_001100613
780
85507
S310
H
P
V
S
M
N
N
S
N
H
L
V
N
S
D
Dog
Lupus familis
XP_861054
780
85672
S310
H
P
V
S
M
N
N
S
N
H
L
V
N
S
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JHE3
756
83491
Y297
V
N
S
D
N
M
G
Y
A
A
Y
L
F
E
Q
Rat
Rattus norvegicus
Q91XT9
761
83469
D298
S
N
H
L
V
N
S
D
N
M
G
Y
A
A
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506611
746
81905
Y287
V
N
S
D
N
V
G
Y
A
S
Y
L
F
E
Q
Chicken
Gallus gallus
XP_421560
811
88602
T344
H
P
V
S
M
N
N
T
N
H
L
V
N
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5W7F1
743
82050
F283
L
G
Y
A
S
Y
I
F
E
Q
E
K
N
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA70
704
78213
A245
S
D
N
V
G
Y
A
A
L
L
L
E
K
E
Y
Honey Bee
Apis mellifera
XP_393129
717
79852
N258
L
F
E
R
I
M
N
N
D
S
L
I
G
K
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q304B9
757
83246
S298
Y
K
S
S
R
G
H
S
V
D
K
S
L
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.2
84.8
N.A.
79.2
79.4
N.A.
73.5
62.6
N.A.
57.3
N.A.
40.9
41
N.A.
N.A.
Protein Similarity:
100
99.3
97.8
91.7
N.A.
88
89.2
N.A.
83.7
73.2
N.A.
70.6
N.A.
57.1
57.3
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
0
13.3
N.A.
0
93.3
N.A.
6.6
N.A.
6.6
13.3
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
6.6
33.3
N.A.
6.6
100
N.A.
13.3
N.A.
13.3
40
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.9
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
9
9
17
9
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
17
0
0
0
9
9
9
0
0
0
9
42
% D
% Glu:
0
0
9
0
0
0
0
0
9
0
9
9
0
25
0
% E
% Phe:
0
9
0
0
0
0
0
9
0
0
0
0
17
0
0
% F
% Gly:
0
9
0
0
9
9
17
0
0
0
9
0
9
0
17
% G
% His:
42
0
9
0
0
0
9
0
0
42
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
0
0
0
9
0
9
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
9
9
9
0
% K
% Leu:
17
0
0
9
0
0
0
0
9
9
59
17
9
0
0
% L
% Met:
0
0
0
0
42
17
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
25
9
0
17
50
50
9
50
0
0
0
50
0
0
% N
% Pro:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
17
% Q
% Arg:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
17
0
25
50
9
0
9
42
0
17
0
9
0
42
0
% S
% Thr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
17
0
42
9
9
9
0
0
9
0
0
42
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
17
0
17
0
0
17
9
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _