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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASAH2 All Species: 17.27
Human Site: Y666 Identified Species: 34.55
UniProt: Q9NR71 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR71 NP_001072984.1 780 85516 Y666 L Q P A K P E Y R V G E V A E
Chimpanzee Pan troglodytes XP_507791 780 85671 Y666 L Q P A K P E Y R V G E V A E
Rhesus Macaque Macaca mulatta XP_001100613 780 85507 Y666 L Q P A K P E Y R V G E V A E
Dog Lupus familis XP_861054 780 85672 Y666 L Q P A K P T Y R V G E V A E
Cat Felis silvestris
Mouse Mus musculus Q9JHE3 756 83491 V648 E Y R V G E V V E V I F V G A
Rat Rattus norvegicus Q91XT9 761 83469 G650 A K P E Y R V G E V V E V V F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506611 746 81905 A638 Q Y R R G D V A E V S F V G A
Chicken Gallus gallus XP_421560 811 88602 Y701 L Q G V N V Q Y R A G E V A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q5W7F1 743 82050 S634 Y K V G E I A S V T F V S G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VA70 704 78213 G596 S Q P N K E Y G I N E T V K V
Honey Bee Apis mellifera XP_393129 717 79852 S609 I V T A V F V S G H P R N N L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q304B9 757 83246 T649 A D V P P K S T F R R G Q Q V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 96.2 84.8 N.A. 79.2 79.4 N.A. 73.5 62.6 N.A. 57.3 N.A. 40.9 41 N.A. N.A.
Protein Similarity: 100 99.3 97.8 91.7 N.A. 88 89.2 N.A. 83.7 73.2 N.A. 70.6 N.A. 57.1 57.3 N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 13.3 26.6 N.A. 13.3 53.3 N.A. 0 N.A. 26.6 6.6 N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 33.3 N.A. 13.3 60 N.A. 13.3 N.A. 26.6 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 48.9 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 42 0 0 9 9 0 9 0 0 0 42 25 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 0 0 9 9 17 25 0 25 0 9 50 0 0 34 % E
% Phe: 0 0 0 0 0 9 0 0 9 0 9 17 0 0 9 % F
% Gly: 0 0 9 9 17 0 0 17 9 0 42 9 0 25 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 9 0 0 9 0 9 0 0 0 0 % I
% Lys: 0 17 0 0 42 9 0 0 0 0 0 0 0 9 0 % K
% Leu: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 0 0 0 9 0 0 9 9 9 % N
% Pro: 0 0 50 9 9 34 0 0 0 0 9 0 0 0 0 % P
% Gln: 9 50 0 0 0 0 9 0 0 0 0 0 9 9 0 % Q
% Arg: 0 0 17 9 0 9 0 0 42 9 9 9 0 0 0 % R
% Ser: 9 0 0 0 0 0 9 17 0 0 9 0 9 0 0 % S
% Thr: 0 0 9 0 0 0 9 9 0 9 0 9 0 0 0 % T
% Val: 0 9 17 17 9 9 34 9 9 59 9 9 75 9 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 17 0 0 9 0 9 42 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _