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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF4
All Species:
2.42
Human Site:
T108
Identified Species:
10.67
UniProt:
Q9NR80
Number Species:
5
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR80
NP_056135.2
690
79067
T108
C
W
R
K
T
I
I
T
S
P
E
S
L
N
L
Chimpanzee
Pan troglodytes
XP_525919
619
71188
S89
V
R
A
D
E
V
G
S
E
E
D
L
Y
D
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_540976
566
64863
N61
G
G
E
Q
L
A
I
N
E
L
I
S
D
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNR9
484
56661
Rat
Rattus norvegicus
Q9QX73
493
58139
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422582
594
69364
S88
L
A
I
N
E
L
I
S
D
G
S
V
V
Y
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.4
N.A.
76
N.A.
65.3
42
N.A.
N.A.
66
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
85
N.A.
78.6
N.A.
67.3
55.5
N.A.
N.A.
75.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
N.A.
13.3
N.A.
0
0
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
20
N.A.
0
0
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
17
0
0
17
0
0
0
0
0
0
0
0
17
% A
% Cys:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
17
0
0
0
0
17
0
17
0
17
17
17
% D
% Glu:
0
0
17
0
34
0
0
0
34
17
17
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
17
0
0
0
0
17
0
0
17
0
0
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
17
50
0
0
0
17
0
0
0
0
% I
% Lys:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
0
0
0
17
17
0
0
0
17
0
17
17
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
17
0
0
0
17
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% P
% Gln:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
17
17
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
34
17
0
17
34
0
0
17
% S
% Thr:
0
0
0
0
17
0
0
17
0
0
0
0
0
0
0
% T
% Val:
17
0
0
0
0
17
0
0
0
0
0
17
17
0
0
% V
% Trp:
0
17
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
17
17
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _