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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGEF3
All Species:
10.61
Human Site:
S466
Identified Species:
25.93
UniProt:
Q9NR81
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR81
NP_001122087.1
526
59783
S466
G
V
L
D
S
E
G
S
F
L
N
P
T
T
G
Chimpanzee
Pan troglodytes
XP_001173620
527
60080
S467
G
V
L
D
S
E
G
S
F
L
N
P
T
T
G
Rhesus Macaque
Macaca mulatta
XP_001101312
526
59692
S466
G
V
L
D
S
E
G
S
F
L
N
P
T
T
G
Dog
Lupus familis
XP_533783
902
100624
P842
G
D
L
D
S
E
G
P
F
L
N
P
A
T
G
Cat
Felis silvestris
Mouse
Mus musculus
Q91X46
524
59508
L465
G
L
L
D
S
E
G
L
V
Q
G
P
G
T
E
Rat
Rattus norvegicus
NP_001099531
524
59627
L465
G
L
L
D
S
E
S
L
S
Q
S
P
G
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511179
542
61966
P476
E
E
N
N
P
A
V
P
N
V
Q
A
H
R
R
Chicken
Gallus gallus
Q5ZLX4
524
59980
C465
G
V
L
S
S
E
A
C
F
I
L
S
P
N
G
Frog
Xenopus laevis
NP_001090143
523
60117
S462
G
G
D
D
A
S
S
S
N
R
R
L
S
I
S
Zebra Danio
Brachydanio rerio
NP_001076337
506
58471
I446
K
Q
Q
W
L
N
C
I
R
Q
A
K
E
A
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.6
99.6
57
N.A.
94.4
93.9
N.A.
55.7
87
79.4
73.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.6
99.6
57.4
N.A.
95.8
96
N.A.
70.8
93.5
86.1
82.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
53.3
46.6
N.A.
0
46.6
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
80
N.A.
60
60
N.A.
13.3
53.3
33.3
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
10
10
0
0
0
10
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
70
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
0
0
0
70
0
0
0
0
0
0
10
0
20
% E
% Phe:
0
0
0
0
0
0
0
0
50
0
0
0
0
0
0
% F
% Gly:
80
10
0
0
0
0
50
0
0
0
10
0
20
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
10
0
0
0
10
0
% I
% Lys:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% K
% Leu:
0
20
70
0
10
0
0
20
0
40
10
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
10
0
10
0
0
20
0
40
0
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
20
0
0
0
60
10
0
0
% P
% Gln:
0
10
10
0
0
0
0
0
0
30
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
10
10
0
0
10
10
% R
% Ser:
0
0
0
10
70
10
20
40
10
0
10
10
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
30
60
0
% T
% Val:
0
40
0
0
0
0
10
0
10
10
0
0
0
0
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _