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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLR8
All Species:
14.55
Human Site:
S368
Identified Species:
45.71
UniProt:
Q9NR97
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NR97
NP_619542.1
1041
119828
S368
R
N
F
S
K
L
L
S
L
R
A
L
H
L
R
Chimpanzee
Pan troglodytes
B3Y613
784
89806
L176
D
F
A
G
L
T
F
L
E
E
L
E
I
D
A
Rhesus Macaque
Macaca mulatta
B3Y618
784
90053
L176
D
F
A
G
L
T
F
L
E
E
L
E
I
D
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P58682
1032
119320
S363
S
N
F
S
K
L
R
S
L
K
K
L
H
L
R
Rat
Rattus norvegicus
NP_001094479
1029
119254
S360
P
N
F
S
M
L
R
S
L
R
K
L
H
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515241
1264
142802
S584
D
N
F
S
K
L
V
S
L
Q
A
L
H
V
K
Chicken
Gallus gallus
Q9DD78
793
90748
F185
G
N
F
E
G
I
V
F
L
N
T
L
R
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002665957
1231
140895
S549
E
S
F
S
Q
L
K
S
L
R
V
L
R
I
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
24.9
24.3
N.A.
N.A.
71.1
70.9
N.A.
52.2
24.6
N.A.
38.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
40.9
39.6
N.A.
N.A.
82.3
82.3
N.A.
64.7
40.5
N.A.
55.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
N.A.
N.A.
73.3
66.6
N.A.
66.6
26.6
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
0
N.A.
N.A.
80
73.3
N.A.
93.3
46.6
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
0
0
0
25
0
0
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
38
0
0
0
0
0
0
0
0
0
0
0
0
25
13
% D
% Glu:
13
0
0
13
0
0
0
0
25
25
0
25
0
0
0
% E
% Phe:
0
25
75
0
0
0
25
13
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
25
13
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
50
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
0
0
25
25
0
% I
% Lys:
0
0
0
0
38
0
13
0
0
13
25
0
0
0
25
% K
% Leu:
0
0
0
0
25
63
13
25
75
0
25
75
0
38
0
% L
% Met:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
63
0
0
0
0
0
0
0
13
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
13
0
0
0
0
0
% Q
% Arg:
13
0
0
0
0
0
25
0
0
38
0
0
25
0
38
% R
% Ser:
13
13
0
63
0
0
0
63
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
25
0
0
0
0
13
0
0
0
0
% T
% Val:
0
0
0
0
0
0
25
0
0
0
13
0
0
13
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _