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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 9.39
Human Site: S16 Identified Species: 15.9
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 S16 A R N D G E E S T D R T P L L
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 S16 A R N D G E E S T D R T P L L
Dog Lupus familis XP_532204 495 54438 G16 A S S D G E E G S D R T P L L
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 S16 A G N D D E E S S D S T P L L
Rat Rattus norvegicus Q7TSF2 588 64736 L29 K N A V G D S L G I L Q R K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 P12 H G W R A E E P F Q S K C L P
Chicken Gallus gallus NP_001026257 484 53539 S16 R T P L L K E S Q L G T V P A
Frog Xenopus laevis Q6INC8 576 63887 L16 K K L A G N T L G H L H R I L
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 L28 K N N V G D S L G N L Q K K I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 L18 R H R D G H V L V W N Q R N L
Honey Bee Apis mellifera XP_395682 508 56831 E16 S V D F I V L E T M E R K K S
Nematode Worm Caenorhab. elegans Q03567 493 52719 F16 R L V P S T R F A L S L V M F
Sea Urchin Strong. purpuratus XP_780445 542 58846 P19 S K K A V K A P R P S G G K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 G29 C Q R L G K S G A E V S K L F
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 73.3 N.A. 73.3 13.3 N.A. 20 20 13.3 13.3 N.A. 20 6.6 0 0
P-Site Similarity: 100 N.A. 100 86.6 N.A. 80 20 N.A. 20 26.6 26.6 33.3 N.A. 20 20 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 29 0 8 15 8 0 8 0 15 0 0 0 0 0 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 0 8 36 8 15 0 0 0 29 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 36 43 8 0 8 8 0 0 0 0 % E
% Phe: 0 0 0 8 0 0 0 8 8 0 0 0 0 0 15 % F
% Gly: 0 15 0 0 58 0 0 15 22 0 8 8 8 0 0 % G
% His: 8 8 0 0 0 8 0 0 0 8 0 8 0 0 0 % H
% Ile: 0 0 0 0 8 0 0 0 0 8 0 0 0 8 8 % I
% Lys: 22 15 8 0 0 22 0 0 0 0 0 8 22 29 8 % K
% Leu: 0 8 8 15 8 0 8 29 0 15 22 8 0 43 50 % L
% Met: 0 0 0 0 0 0 0 0 0 8 0 0 0 8 0 % M
% Asn: 0 15 29 0 0 8 0 0 0 8 8 0 0 8 0 % N
% Pro: 0 0 8 8 0 0 0 15 0 8 0 0 29 8 8 % P
% Gln: 0 8 0 0 0 0 0 0 8 8 0 22 0 0 0 % Q
% Arg: 22 15 15 8 0 0 8 0 8 0 22 8 22 0 0 % R
% Ser: 15 8 8 0 8 0 22 29 15 0 29 8 0 0 8 % S
% Thr: 0 8 0 0 0 8 8 0 22 0 0 36 0 0 0 % T
% Val: 0 8 8 15 8 8 8 0 8 0 8 0 15 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _