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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 41.52
Human Site: S196 Identified Species: 70.26
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 S196 W A P P L E R S K L L S I S Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 S196 W A P P L E R S K L L S I S Y
Dog Lupus familis XP_532204 495 54438 S196 W A P P L E R S K L L S I S Y
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 S196 W A P P L E R S K L L T I S Y
Rat Rattus norvegicus Q7TSF2 588 64736 S217 W A P P L E R S R L A T T S F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 F180 G G K L L L G F G I L G T A V
Chicken Gallus gallus NP_001026257 484 53539 S185 W A P P L E R S K L L S I S Y
Frog Xenopus laevis Q6INC8 576 63887 S204 W A P P L E R S R L A T T A F
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 S217 W A P P L E R S R L A T T S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 A201 N E R S R M G A A V Y A G A Q
Honey Bee Apis mellifera XP_395682 508 56831 S195 W A P P L E R S K L A T I T F
Nematode Worm Caenorhab. elegans Q03567 493 52719 N185 Y A G A Q I G N V I V L P L S
Sea Urchin Strong. purpuratus XP_780445 542 58846 S199 W A P P V E R S R L L T F T Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 S258 W I P V S E R S R S L A L V Y
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 100 N.A. 93.3 66.6 N.A. 13.3 100 60 66.6 N.A. 0 73.3 6.6 66.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 86.6 N.A. 26.6 100 86.6 86.6 N.A. 26.6 93.3 33.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 79 0 8 0 0 0 8 8 0 29 15 0 22 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 8 0 0 0 79 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 29 % F
% Gly: 8 8 8 0 0 0 22 0 8 0 0 8 8 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 8 0 0 0 15 0 0 43 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 43 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 72 8 0 0 0 72 58 8 8 8 0 % L
% Met: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 79 72 0 0 0 0 0 0 0 0 8 0 0 % P
% Gln: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % Q
% Arg: 0 0 8 0 8 0 79 0 36 0 0 0 0 0 0 % R
% Ser: 0 0 0 8 8 0 0 79 0 8 0 29 0 50 8 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 43 29 15 0 % T
% Val: 0 0 0 8 8 0 0 0 8 8 8 0 0 8 8 % V
% Trp: 79 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 50 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _