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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC17A5 All Species: 12.42
Human Site: T17 Identified Species: 21.03
UniProt: Q9NRA2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA2 NP_036566.1 495 54640 T17 R N D G E E S T D R T P L L P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001112868 495 54586 T17 R N D G E E S T D R T P L L P
Dog Lupus familis XP_532204 495 54438 S17 S S D G E E G S D R T P L L Q
Cat Felis silvestris
Mouse Mus musculus Q8BN82 495 54351 S17 G N D D E E S S D S T P L L P
Rat Rattus norvegicus Q7TSF2 588 64736 G30 N A V G D S L G I L Q R K L D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506458 459 50560 F13 G W R A E E P F Q S K C L P R
Chicken Gallus gallus NP_001026257 484 53539 Q17 T P L L K E S Q L G T V P A C
Frog Xenopus laevis Q6INC8 576 63887 G17 K L A G N T L G H L H R I L E
Zebra Danio Brachydanio rerio Q1L8X9 590 64796 G29 N N V G D S L G N L Q K K I D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V7S5 529 58354 V19 H R D G H V L V W N Q R N L H
Honey Bee Apis mellifera XP_395682 508 56831 T17 V D F I V L E T M E R K K S S
Nematode Worm Caenorhab. elegans Q03567 493 52719 A17 L V P S T R F A L S L V M F F
Sea Urchin Strong. purpuratus XP_780445 542 58846 R20 K K A V K A P R P S G G K K R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8GX78 541 59595 A30 Q R L G K S G A E V S K L F P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.7 89.2 N.A. 86.2 31.6 N.A. 61.4 77.7 31.9 32.5 N.A. 36.6 38.5 40.2 42.6
Protein Similarity: 100 N.A. 99.8 94.3 N.A. 92.7 48.6 N.A. 69.4 87.2 47.9 48.9 N.A. 52.5 57.4 59.3 62.1
P-Site Identity: 100 N.A. 100 66.6 N.A. 73.3 13.3 N.A. 20 20 13.3 13.3 N.A. 20 6.6 0 0
P-Site Similarity: 100 N.A. 100 80 N.A. 80 20 N.A. 20 26.6 26.6 33.3 N.A. 20 13.3 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. 32.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 49.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 15 8 0 8 0 15 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % C
% Asp: 0 8 36 8 15 0 0 0 29 0 0 0 0 0 15 % D
% Glu: 0 0 0 0 36 43 8 0 8 8 0 0 0 0 8 % E
% Phe: 0 0 8 0 0 0 8 8 0 0 0 0 0 15 8 % F
% Gly: 15 0 0 58 0 0 15 22 0 8 8 8 0 0 0 % G
% His: 8 0 0 0 8 0 0 0 8 0 8 0 0 0 8 % H
% Ile: 0 0 0 8 0 0 0 0 8 0 0 0 8 8 0 % I
% Lys: 15 8 0 0 22 0 0 0 0 0 8 22 29 8 0 % K
% Leu: 8 8 15 8 0 8 29 0 15 22 8 0 43 50 0 % L
% Met: 0 0 0 0 0 0 0 0 8 0 0 0 8 0 0 % M
% Asn: 15 29 0 0 8 0 0 0 8 8 0 0 8 0 0 % N
% Pro: 0 8 8 0 0 0 15 0 8 0 0 29 8 8 29 % P
% Gln: 8 0 0 0 0 0 0 8 8 0 22 0 0 0 8 % Q
% Arg: 15 15 8 0 0 8 0 8 0 22 8 22 0 0 15 % R
% Ser: 8 8 0 8 0 22 29 15 0 29 8 0 0 8 8 % S
% Thr: 8 0 0 0 8 8 0 22 0 0 36 0 0 0 0 % T
% Val: 8 8 15 8 8 8 0 8 0 8 0 15 0 0 0 % V
% Trp: 0 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _