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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF4ENIF1 All Species: 29.39
Human Site: S429 Identified Species: 58.79
UniProt: Q9NRA8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA8 NP_001157973.1 985 108201 S429 K L K E S S H S G V V L S V E
Chimpanzee Pan troglodytes XP_001149434 985 108212 S429 K L K E S S H S G V V L S V E
Rhesus Macaque Macaca mulatta XP_001111584 982 107599 S426 K L K E S S H S G V V L S V E
Dog Lupus familis XP_543492 986 108377 S429 K L K E S S H S G V V L S V E
Cat Felis silvestris
Mouse Mus musculus Q9EST3 983 107966 S428 K L K E S S H S G V V L S V E
Rat Rattus norvegicus NP_001100700 985 108290 S429 K L K E S S H S G V V L S V E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506005 628 67762 S134 A F N K L V S S M K A S G T L
Chicken Gallus gallus XP_415254 1367 148531 S814 K L R E S T H S G V V L S V E
Frog Xenopus laevis NP_001086710 771 85462 P277 L E E V A L P P A H A A D Q E
Zebra Danio Brachydanio rerio NP_001013556 747 83379 V253 R P E S V K E V E C N G G L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122940 1223 137663 N566 N G Q G D A A N T V I P M M K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781676 1583 172338 S586 G G D S P A H S R S G P S I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 93 95.8 N.A. 89.9 90.7 N.A. 53.4 59.9 54.2 44 N.A. N.A. 23.2 N.A. 22.5
Protein Similarity: 100 99.9 95.8 97.8 N.A. 94.8 95.1 N.A. 58 66.1 64.5 55.9 N.A. N.A. 39.6 N.A. 36.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 86.6 6.6 0 N.A. N.A. 6.6 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 20 20 N.A. N.A. 46.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 17 9 0 9 0 17 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 9 0 9 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 9 17 59 0 0 9 0 9 0 0 0 0 0 67 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 17 0 9 0 0 0 0 59 0 9 9 17 0 0 % G
% His: 0 0 0 0 0 0 67 0 0 9 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 0 0 9 0 % I
% Lys: 59 0 50 9 0 9 0 0 0 9 0 0 0 0 9 % K
% Leu: 9 59 0 0 9 9 0 0 0 0 0 59 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 9 9 0 % M
% Asn: 9 0 9 0 0 0 0 9 0 0 9 0 0 0 0 % N
% Pro: 0 9 0 0 9 0 9 9 0 0 0 17 0 0 9 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 9 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 17 59 50 9 75 0 9 0 9 67 0 9 % S
% Thr: 0 0 0 0 0 9 0 0 9 0 0 0 0 9 0 % T
% Val: 0 0 0 9 9 9 0 9 0 67 59 0 0 59 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _