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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EIF4ENIF1 All Species: 26.97
Human Site: T357 Identified Species: 53.94
UniProt: Q9NRA8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRA8 NP_001157973.1 985 108201 T357 R S S S L G S T P H E E L E R
Chimpanzee Pan troglodytes XP_001149434 985 108212 T357 R S S S L G S T P H E E L E R
Rhesus Macaque Macaca mulatta XP_001111584 982 107599 T354 R S S S L G S T P H E E L E R
Dog Lupus familis XP_543492 986 108377 T357 R S S S L G S T P H E E L E R
Cat Felis silvestris
Mouse Mus musculus Q9EST3 983 107966 T356 R S S S L G S T P H E E L E R
Rat Rattus norvegicus NP_001100700 985 108290 T357 R S S S L G S T P H E E L E R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506005 628 67762 E81 G V V L S V E E V E A G L K G
Chicken Gallus gallus XP_415254 1367 148531 T742 R S S S L R S T P H E E L E R
Frog Xenopus laevis NP_001086710 771 85462 G224 E P E W F S A G P T S Q S E T
Zebra Danio Brachydanio rerio NP_001013556 747 83379 R200 R V F S E R R R N D S Y A E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001122940 1223 137663 I494 V D S R R T S I Q D D I L N N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781676 1583 172338 A451 V S M S T Q M A L L G M M Q K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 93 95.8 N.A. 89.9 90.7 N.A. 53.4 59.9 54.2 44 N.A. N.A. 23.2 N.A. 22.5
Protein Similarity: 100 99.9 95.8 97.8 N.A. 94.8 95.1 N.A. 58 66.1 64.5 55.9 N.A. N.A. 39.6 N.A. 36.3
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 93.3 13.3 20 N.A. N.A. 20 N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 93.3 26.6 20 N.A. N.A. 26.6 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 9 9 0 0 9 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 17 9 0 0 0 0 % D
% Glu: 9 0 9 0 9 0 9 9 0 9 59 59 0 75 9 % E
% Phe: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 50 0 9 0 0 9 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 9 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % K
% Leu: 0 0 0 9 59 0 0 0 9 9 0 0 75 0 0 % L
% Met: 0 0 9 0 0 0 9 0 0 0 0 9 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 9 0 0 0 0 9 9 % N
% Pro: 0 9 0 0 0 0 0 0 67 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 9 0 0 9 0 9 0 % Q
% Arg: 67 0 0 9 9 17 9 9 0 0 0 0 0 0 59 % R
% Ser: 0 67 67 75 9 9 67 0 0 0 17 0 9 0 0 % S
% Thr: 0 0 0 0 9 9 0 59 0 9 0 0 0 0 9 % T
% Val: 17 17 9 0 0 9 0 0 9 0 0 0 0 0 0 % V
% Trp: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _