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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF4ENIF1
All Species:
24.24
Human Site:
T465
Identified Species:
48.48
UniProt:
Q9NRA8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRA8
NP_001157973.1
985
108201
T465
M
A
E
H
L
E
E
T
L
S
A
V
T
N
N
Chimpanzee
Pan troglodytes
XP_001149434
985
108212
T465
M
A
E
H
L
E
E
T
L
S
A
V
T
N
N
Rhesus Macaque
Macaca mulatta
XP_001111584
982
107599
T462
M
A
E
H
L
E
E
T
L
S
A
V
T
N
N
Dog
Lupus familis
XP_543492
986
108377
T465
M
A
E
H
L
E
E
T
L
S
A
V
T
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9EST3
983
107966
T464
M
A
E
H
L
E
E
T
L
S
A
A
S
S
N
Rat
Rattus norvegicus
NP_001100700
985
108290
T465
M
A
E
H
L
E
E
T
L
S
A
V
T
S
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506005
628
67762
P165
H
P
E
I
P
S
Q
P
L
P
K
N
I
L
Q
Chicken
Gallus gallus
XP_415254
1367
148531
E849
F
M
A
E
Q
M
E
E
S
L
N
I
A
G
S
Frog
Xenopus laevis
NP_001086710
771
85462
D308
F
N
E
F
F
N
L
D
K
S
V
P
G
L
A
Zebra Danio
Brachydanio rerio
NP_001013556
747
83379
T284
H
A
E
L
P
E
Q
T
P
G
D
F
D
F
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122940
1223
137663
P604
M
R
G
G
V
P
P
P
T
S
S
T
D
Q
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781676
1583
172338
R672
P
H
P
G
L
G
L
R
T
A
S
P
P
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
93
95.8
N.A.
89.9
90.7
N.A.
53.4
59.9
54.2
44
N.A.
N.A.
23.2
N.A.
22.5
Protein Similarity:
100
99.9
95.8
97.8
N.A.
94.8
95.1
N.A.
58
66.1
64.5
55.9
N.A.
N.A.
39.6
N.A.
36.3
P-Site Identity:
100
100
100
93.3
N.A.
80
93.3
N.A.
13.3
6.6
13.3
33.3
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
100
N.A.
20
20
13.3
40
N.A.
N.A.
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
9
0
0
0
0
0
0
9
50
9
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
9
0
17
0
0
% D
% Glu:
0
0
75
9
0
59
59
9
0
0
0
0
0
0
0
% E
% Phe:
17
0
0
9
9
0
0
0
0
0
0
9
0
9
0
% F
% Gly:
0
0
9
17
0
9
0
0
0
9
0
0
9
9
9
% G
% His:
17
9
0
50
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% K
% Leu:
0
0
0
9
59
0
17
0
59
9
0
0
0
17
0
% L
% Met:
59
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
9
0
0
0
0
9
9
0
25
59
% N
% Pro:
9
9
9
0
17
9
9
17
9
9
0
17
9
9
9
% P
% Gln:
0
0
0
0
9
0
17
0
0
0
0
0
0
9
9
% Q
% Arg:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
9
67
17
0
9
25
9
% S
% Thr:
0
0
0
0
0
0
0
59
17
0
0
9
42
0
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
9
42
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _