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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SIRT7 All Species: 37.58
Human Site: S166 Identified Species: 75.15
UniProt: Q9NRC8 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NRC8 NP_057622.1 400 44898 S166 K L V Q H V V S Q N C D G L H
Chimpanzee Pan troglodytes XP_511750 400 44852 S166 K L V Q H V V S Q N C D G L H
Rhesus Macaque Macaca mulatta XP_001112687 400 44866 S166 K L V Q H V V S Q N C D G L H
Dog Lupus familis XP_540490 400 44926 S166 K L V Q H V V S Q N C D G L H
Cat Felis silvestris
Mouse Mus musculus Q8BKJ9 402 45127 S167 K L V Q H V V S Q N C D G L H
Rat Rattus norvegicus NP_001100543 402 45094 S167 K L V Q H V V S Q N C D G L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001026277 399 45041 S167 N L V Q H V V S Q N C D G L H
Frog Xenopus laevis NP_001088383 393 44588 S161 G M V H H V V S Q N C D G L H
Zebra Danio Brachydanio rerio XP_001336438 372 42111 T152 S Q A E P T L T H M S I W M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651664 771 88450 S190 R L L H H V V S Q N C D G L H
Honey Bee Apis mellifera XP_397168 374 42884 A156 L T H M A L Y A L Y K A R V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198553 311 35331 Y95 T A A S I P D Y R G P N G V W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 99.5 94 N.A. 94.2 93.5 N.A. N.A. 76.2 62.7 56.7 N.A. 29.4 50.5 N.A. 46.2
Protein Similarity: 100 100 100 96.5 N.A. 96.5 96 N.A. N.A. 85 74.2 68.7 N.A. 37.4 66.7 N.A. 59.2
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 80 0 N.A. 80 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 26.6 N.A. 93.3 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 9 0 0 9 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 75 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 9 0 0 0 0 75 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 9 0 0 84 0 0 % G
% His: 0 0 9 17 75 0 0 0 9 0 0 0 0 0 75 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 50 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 9 67 9 0 0 9 9 0 9 0 0 0 0 75 17 % L
% Met: 0 9 0 9 0 0 0 0 0 9 0 0 0 9 0 % M
% Asn: 9 0 0 0 0 0 0 0 0 75 0 9 0 0 0 % N
% Pro: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 0 % P
% Gln: 0 9 0 59 0 0 0 0 75 0 0 0 0 0 0 % Q
% Arg: 9 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % R
% Ser: 9 0 0 9 0 0 0 75 0 0 9 0 0 0 0 % S
% Thr: 9 9 0 0 0 9 0 9 0 0 0 0 0 0 0 % T
% Val: 0 0 67 0 0 75 75 0 0 0 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % W
% Tyr: 0 0 0 0 0 0 9 9 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _