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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIRT7
All Species:
24.24
Human Site:
S65
Identified Species:
48.48
UniProt:
Q9NRC8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRC8
NP_057622.1
400
44898
S65
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Chimpanzee
Pan troglodytes
XP_511750
400
44852
S65
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Rhesus Macaque
Macaca mulatta
XP_001112687
400
44866
S65
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Dog
Lupus familis
XP_540490
400
44926
S65
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKJ9
402
45127
S66
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Rat
Rattus norvegicus
NP_001100543
402
45094
S66
V
T
E
L
Q
G
R
S
R
R
R
E
G
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026277
399
45041
R66
V
R
E
L
E
R
R
R
K
R
R
E
R
L
R
Frog
Xenopus laevis
NP_001088383
393
44588
K60
V
H
E
S
E
R
R
K
L
H
S
E
R
R
R
Zebra Danio
Brachydanio rerio
XP_001336438
372
42111
T61
M
L
Q
A
H
Q
D
T
V
Q
E
L
S
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651664
771
88450
K89
V
K
T
T
K
K
R
K
E
R
V
E
I
Y
K
Honey Bee
Apis mellifera
XP_397168
374
42884
Q67
V
K
E
V
N
L
R
Q
E
K
R
H
R
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198553
311
35331
V8
M
S
E
S
N
L
H
V
R
A
I
L
K
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
94
N.A.
94.2
93.5
N.A.
N.A.
76.2
62.7
56.7
N.A.
29.4
50.5
N.A.
46.2
Protein Similarity:
100
100
100
96.5
N.A.
96.5
96
N.A.
N.A.
85
74.2
68.7
N.A.
37.4
66.7
N.A.
59.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
53.3
26.6
0
N.A.
33.3
33.3
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
73.3
40
33.3
N.A.
40
53.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
84
0
17
0
0
0
17
0
9
75
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
50
0
0
0
0
0
0
50
0
0
% G
% His:
0
9
0
0
9
0
9
0
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% I
% Lys:
0
17
0
0
9
9
0
17
9
9
0
0
9
9
67
% K
% Leu:
0
9
0
59
0
17
0
0
9
0
0
17
0
59
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
0
50
9
0
9
0
9
0
0
0
0
0
% Q
% Arg:
0
9
0
0
0
17
84
9
59
67
67
0
25
17
25
% R
% Ser:
0
9
0
17
0
0
0
50
0
0
9
0
9
0
0
% S
% Thr:
0
50
9
9
0
0
0
9
0
0
0
0
0
0
0
% T
% Val:
84
0
0
9
0
0
0
9
9
0
9
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _