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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIRT7
All Species:
36.06
Human Site:
T127
Identified Species:
72.12
UniProt:
Q9NRC8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRC8
NP_057622.1
400
44898
T127
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
S
Chimpanzee
Pan troglodytes
XP_511750
400
44852
T127
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
S
Rhesus Macaque
Macaca mulatta
XP_001112687
400
44866
T127
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
S
Dog
Lupus familis
XP_540490
400
44926
T127
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKJ9
402
45127
T128
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
P
Rat
Rattus norvegicus
NP_001100543
402
45094
T128
R
G
P
N
G
V
W
T
L
L
Q
K
G
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026277
399
45041
T128
R
G
P
N
G
I
W
T
L
L
Q
K
G
R
S
Frog
Xenopus laevis
NP_001088383
393
44588
T122
R
G
P
S
G
V
W
T
L
L
N
K
G
R
T
Zebra Danio
Brachydanio rerio
XP_001336438
372
42111
G113
L
V
I
Y
T
G
A
G
I
S
T
A
A
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651664
771
88450
T151
R
G
S
Q
G
I
W
T
L
L
Q
K
G
Q
D
Honey Bee
Apis mellifera
XP_397168
374
42884
S117
A
G
I
S
T
A
A
S
I
P
D
Y
R
G
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198553
311
35331
D56
Q
K
S
Q
E
V
E
D
S
V
G
E
L
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
94
N.A.
94.2
93.5
N.A.
N.A.
76.2
62.7
56.7
N.A.
29.4
50.5
N.A.
46.2
Protein Similarity:
100
100
100
96.5
N.A.
96.5
96
N.A.
N.A.
85
74.2
68.7
N.A.
37.4
66.7
N.A.
59.2
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
80
0
N.A.
66.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
100
93.3
6.6
N.A.
80
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
9
17
0
0
0
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
9
% D
% Glu:
0
0
0
0
9
0
9
0
0
0
0
9
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
84
0
0
75
9
0
9
0
0
9
0
75
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
17
0
0
17
0
0
17
0
0
0
0
0
17
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
0
75
0
0
0
% K
% Leu:
9
0
0
0
0
0
0
0
75
75
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
59
0
0
0
0
0
0
9
0
0
0
0
% N
% Pro:
0
0
67
0
0
0
0
0
0
9
0
0
0
0
17
% P
% Gln:
9
0
0
17
0
0
0
0
0
0
67
0
0
9
0
% Q
% Arg:
75
0
0
0
0
0
0
0
0
0
0
0
9
67
0
% R
% Ser:
0
0
17
17
0
0
0
9
9
9
0
0
0
9
42
% S
% Thr:
0
0
0
0
17
0
0
75
0
0
9
0
0
0
17
% T
% Val:
0
9
0
0
0
67
0
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
75
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _