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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIRT7
All Species:
33.03
Human Site:
Y204
Identified Species:
66.06
UniProt:
Q9NRC8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRC8
NP_057622.1
400
44898
Y204
S
C
V
P
N
R
E
Y
V
R
V
F
D
V
T
Chimpanzee
Pan troglodytes
XP_511750
400
44852
Y204
S
C
V
P
N
R
E
Y
V
R
V
F
D
V
T
Rhesus Macaque
Macaca mulatta
XP_001112687
400
44866
Y204
S
C
I
P
N
R
E
Y
V
R
V
F
D
V
T
Dog
Lupus familis
XP_540490
400
44926
Y204
A
C
T
P
N
R
E
Y
V
R
V
F
D
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKJ9
402
45127
Y205
S
C
I
P
N
R
E
Y
V
R
V
F
D
V
T
Rat
Rattus norvegicus
NP_001100543
402
45094
Y205
S
C
I
P
N
R
E
Y
V
R
V
F
D
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026277
399
45041
Y205
S
C
T
P
N
R
E
Y
V
R
V
F
D
V
T
Frog
Xenopus laevis
NP_001088383
393
44588
Y199
L
C
S
P
Q
K
E
Y
V
R
V
F
D
V
T
Zebra Danio
Brachydanio rerio
XP_001336438
372
42111
H190
E
R
T
A
L
H
R
H
G
T
G
R
S
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651664
771
88450
Y228
N
C
R
P
N
S
V
Y
W
R
Q
F
D
T
T
Honey Bee
Apis mellifera
XP_397168
374
42884
V194
E
V
H
G
N
M
Y
V
E
V
C
R
I
C
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198553
311
35331
E133
M
A
L
A
R
L
V
E
E
G
M
V
K
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.5
94
N.A.
94.2
93.5
N.A.
N.A.
76.2
62.7
56.7
N.A.
29.4
50.5
N.A.
46.2
Protein Similarity:
100
100
100
96.5
N.A.
96.5
96
N.A.
N.A.
85
74.2
68.7
N.A.
37.4
66.7
N.A.
59.2
P-Site Identity:
100
100
93.3
86.6
N.A.
93.3
93.3
N.A.
N.A.
93.3
73.3
0
N.A.
53.3
6.6
N.A.
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
93.3
80
6.6
N.A.
60
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
75
0
0
0
0
0
0
0
0
9
0
0
17
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
75
0
0
% D
% Glu:
17
0
0
0
0
0
67
9
17
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
75
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
9
9
9
0
0
0
0
% G
% His:
0
0
9
0
0
9
0
9
0
0
0
0
0
9
0
% H
% Ile:
0
0
25
0
0
0
0
0
0
0
0
0
9
0
9
% I
% Lys:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
9
% K
% Leu:
9
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% L
% Met:
9
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
75
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
9
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
9
9
0
9
59
9
0
0
75
0
17
0
0
0
% R
% Ser:
50
0
9
0
0
9
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
25
0
0
0
0
0
0
9
0
0
0
9
75
% T
% Val:
0
9
17
0
0
0
17
9
67
9
67
9
0
67
0
% V
% Trp:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
75
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _