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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO8
All Species:
23.94
Human Site:
S166
Identified Species:
65.83
UniProt:
Q9NRD0
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD0
NP_036312.2
319
37068
S166
S
K
G
I
L
D
D
S
P
K
E
I
A
K
F
Chimpanzee
Pan troglodytes
XP_517540
458
52475
S305
S
K
G
I
L
D
D
S
P
K
E
I
A
K
F
Rhesus Macaque
Macaca mulatta
XP_001087766
513
58067
S360
S
K
G
I
L
D
D
S
P
K
E
I
A
K
F
Dog
Lupus familis
XP_534554
278
32399
W141
F
C
T
R
T
L
N
W
K
K
L
R
I
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZN3
319
36964
S166
S
K
G
I
L
D
D
S
P
K
E
I
A
K
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505866
320
36952
S167
S
K
G
I
I
D
D
S
P
K
E
I
A
K
F
Chicken
Gallus gallus
NP_001006446
319
36891
S166
S
K
G
I
L
D
D
S
P
K
E
I
A
K
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001035397
323
37576
H170
S
R
G
I
L
V
E
H
P
K
E
I
A
K
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785762
294
33822
T150
E
I
A
K
F
I
H
T
T
N
K
L
H
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69.6
61.7
84.9
N.A.
95.6
N.A.
N.A.
93.7
95.9
N.A.
80.1
N.A.
N.A.
N.A.
N.A.
42.9
Protein Similarity:
100
69.6
62.1
86.8
N.A.
97.8
N.A.
N.A.
96.5
97.8
N.A.
87.3
N.A.
N.A.
N.A.
N.A.
60.8
P-Site Identity:
100
100
100
6.6
N.A.
100
N.A.
N.A.
93.3
100
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
13.3
N.A.
100
N.A.
N.A.
100
100
N.A.
86.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
0
0
0
0
0
0
0
0
0
78
0
0
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
67
0
0
0
0
0
0
0
0
% D
% Glu:
12
0
0
0
0
0
12
0
0
0
78
0
0
0
0
% E
% Phe:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
78
% F
% Gly:
0
0
78
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
12
0
0
0
0
12
0
0
% H
% Ile:
0
12
0
78
12
12
0
0
0
0
0
78
12
0
0
% I
% Lys:
0
67
0
12
0
0
0
0
12
89
12
0
0
78
0
% K
% Leu:
0
0
0
0
67
12
0
0
0
0
12
12
0
0
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
78
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
12
0
0
0
0
0
0
0
12
0
12
12
% R
% Ser:
78
0
0
0
0
0
0
67
0
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
12
0
0
12
12
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _