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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PICK1
All Species:
5.45
Human Site:
T399
Identified Species:
10.91
UniProt:
Q9NRD5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD5
NP_001034672.1
415
46600
T399
A
G
E
P
S
R
D
T
R
G
A
A
G
P
L
Chimpanzee
Pan troglodytes
XP_525653
602
66274
T586
A
G
E
P
S
R
D
T
R
G
A
A
G
P
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852720
417
46777
A401
T
G
E
P
S
R
D
A
R
G
A
A
G
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q62083
416
46498
D399
A
A
R
E
V
S
K
D
A
C
G
A
T
G
P
Rat
Rattus norvegicus
Q9EP80
416
46588
A400
A
R
E
V
S
K
D
A
R
G
A
T
G
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519738
348
39327
Q333
H
V
Q
D
I
V
F
Q
R
Q
R
F
V
S
T
Chicken
Gallus gallus
XP_416267
408
45770
E390
E
E
E
G
G
G
S
E
R
E
S
S
G
K
E
Frog
Xenopus laevis
NP_001090147
405
45633
E390
E
E
E
E
D
Q
T
E
K
R
K
E
E
E
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609582
504
56547
V402
P
H
S
T
P
S
Q
V
D
C
G
F
E
A
V
Honey Bee
Apis mellifera
XP_392832
409
45950
T394
E
F
E
S
E
E
K
T
N
I
N
E
D
L
L
Nematode Worm
Caenorhab. elegans
NP_001041046
444
50373
E393
V
L
N
D
N
P
L
E
G
D
L
I
D
V
N
Sea Urchin
Strong. purpuratus
XP_788322
412
46677
N395
E
E
E
E
E
E
N
N
R
G
G
G
G
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.9
N.A.
97.8
N.A.
93.7
96.3
N.A.
77.1
87.4
83.3
N.A.
N.A.
47.4
59.2
44.3
65.7
Protein Similarity:
100
68.9
N.A.
98.8
N.A.
95.6
97.1
N.A.
80
92.2
89.1
N.A.
N.A.
61.5
73.4
61.4
79.5
P-Site Identity:
100
100
N.A.
86.6
N.A.
13.3
60
N.A.
6.6
20
6.6
N.A.
N.A.
0
20
0
26.6
P-Site Similarity:
100
100
N.A.
86.6
N.A.
13.3
66.6
N.A.
13.3
33.3
20
N.A.
N.A.
6.6
20
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
0
0
0
0
0
17
9
0
34
34
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% C
% Asp:
0
0
0
17
9
0
34
9
9
9
0
0
17
0
0
% D
% Glu:
34
25
67
25
17
17
0
25
0
9
0
17
17
9
9
% E
% Phe:
0
9
0
0
0
0
9
0
0
0
0
17
0
0
0
% F
% Gly:
0
25
0
9
9
9
0
0
9
42
25
9
50
17
0
% G
% His:
9
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
0
0
0
9
0
9
0
0
0
% I
% Lys:
0
0
0
0
0
9
17
0
9
0
9
0
0
9
0
% K
% Leu:
0
9
0
0
0
0
9
0
0
0
9
0
0
9
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
9
9
9
0
9
0
0
0
17
% N
% Pro:
9
0
0
25
9
9
0
0
0
0
0
0
0
34
9
% P
% Gln:
0
0
9
0
0
9
9
9
0
9
0
0
0
0
0
% Q
% Arg:
0
9
9
0
0
25
0
0
59
9
9
0
0
0
0
% R
% Ser:
0
0
9
9
34
17
9
0
0
0
9
9
0
9
9
% S
% Thr:
9
0
0
9
0
0
9
25
0
0
0
9
9
0
17
% T
% Val:
9
9
0
9
9
9
0
9
0
0
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _