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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PICK1
All Species:
38.48
Human Site:
Y163
Identified Species:
76.97
UniProt:
Q9NRD5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD5
NP_001034672.1
415
46600
Y163
L
E
R
T
A
E
L
Y
K
G
M
T
E
H
T
Chimpanzee
Pan troglodytes
XP_525653
602
66274
Y349
L
E
R
T
A
E
L
Y
K
G
M
T
E
H
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852720
417
46777
Y163
L
E
R
T
A
E
L
Y
K
G
M
T
E
H
T
Cat
Felis silvestris
Mouse
Mus musculus
Q62083
416
46498
Y163
L
E
R
T
A
E
L
Y
K
G
M
T
E
H
T
Rat
Rattus norvegicus
Q9EP80
416
46588
Y163
L
E
R
T
A
E
L
Y
K
G
M
T
E
H
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519738
348
39327
D115
P
K
Q
G
K
S
L
D
I
V
L
K
K
V
K
Chicken
Gallus gallus
XP_416267
408
45770
Y163
L
E
R
T
A
E
L
Y
K
G
L
T
E
H
T
Frog
Xenopus laevis
NP_001090147
405
45633
Y163
L
E
K
T
G
E
F
Y
R
G
M
M
E
H
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609582
504
56547
Y165
L
E
G
T
E
L
M
Y
K
G
L
V
E
H
A
Honey Bee
Apis mellifera
XP_392832
409
45950
Y163
L
Q
R
T
E
N
L
Y
R
G
L
V
S
H
A
Nematode Worm
Caenorhab. elegans
NP_001041046
444
50373
Y159
L
E
E
N
A
E
F
Y
R
H
L
V
A
Y
F
Sea Urchin
Strong. purpuratus
XP_788322
412
46677
Y159
L
N
K
T
S
R
L
Y
K
G
L
M
D
H
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
68.9
N.A.
97.8
N.A.
93.7
96.3
N.A.
77.1
87.4
83.3
N.A.
N.A.
47.4
59.2
44.3
65.7
Protein Similarity:
100
68.9
N.A.
98.8
N.A.
95.6
97.1
N.A.
80
92.2
89.1
N.A.
N.A.
61.5
73.4
61.4
79.5
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
6.6
93.3
66.6
N.A.
N.A.
53.3
46.6
33.3
53.3
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
33.3
100
80
N.A.
N.A.
66.6
66.6
53.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
59
0
0
0
0
0
0
0
9
0
17
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% D
% Glu:
0
75
9
0
17
67
0
0
0
0
0
0
67
0
0
% E
% Phe:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
9
9
9
0
0
0
0
84
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
84
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
9
17
0
9
0
0
0
67
0
0
9
9
0
9
% K
% Leu:
92
0
0
0
0
9
75
0
0
0
50
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
50
17
0
0
0
% M
% Asn:
0
9
0
9
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
59
0
0
9
0
0
25
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
9
9
0
0
0
0
0
0
9
0
0
% S
% Thr:
0
0
0
84
0
0
0
0
0
0
0
50
0
0
67
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
25
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _