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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
13.94
Human Site:
S1348
Identified Species:
30.67
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.4
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
S1348
T
R
L
R
E
I
Y
S
S
P
K
G
N
G
C
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
S1347
T
R
L
R
E
I
Y
S
S
P
K
G
N
A
C
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
V1197
T
V
P
G
M
T
G
V
L
L
L
L
V
L
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
S1317
T
R
L
R
E
I
Y
S
P
P
V
G
G
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
T1347
T
R
L
R
E
I
Y
T
L
P
L
G
V
D
S
Chicken
Gallus gallus
XP_425053
1523
173782
S1323
T
R
L
R
E
L
Y
S
P
E
S
L
A
L
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
T1142
S
E
L
P
M
K
W
T
F
W
F
F
K
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
D1272
W
K
L
R
N
Y
F
D
P
C
N
Y
N
P
E
Honey Bee
Apis mellifera
XP_624355
1492
172466
D1288
W
K
L
R
N
Y
F
D
P
C
N
Y
N
P
E
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
E1292
W
T
W
K
L
R
S
E
L
I
R
S
L
N
T
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
D1472
M
N
L
R
A
T
Y
D
P
N
V
V
R
E
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
93.3
6.6
N.A.
N.A.
N.A.
66.6
N.A.
60
46.6
N.A.
6.6
N.A.
20
20
0
20
P-Site Similarity:
100
93.3
6.6
N.A.
N.A.
N.A.
66.6
N.A.
66.6
53.3
N.A.
26.6
N.A.
33.3
33.3
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
0
0
0
0
0
0
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
19
% C
% Asp:
0
0
0
0
0
0
0
28
0
0
0
0
0
10
0
% D
% Glu:
0
10
0
0
46
0
0
10
0
10
0
0
0
10
19
% E
% Phe:
0
0
0
0
0
0
19
0
10
0
10
10
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
0
37
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
37
0
0
0
10
0
0
0
0
10
% I
% Lys:
0
19
0
10
0
10
0
0
0
0
19
0
10
0
0
% K
% Leu:
0
0
82
0
10
10
0
0
28
10
19
19
10
19
0
% L
% Met:
10
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
19
0
0
0
0
10
19
0
37
10
0
% N
% Pro:
0
0
10
10
0
0
0
0
46
37
0
0
0
19
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
46
0
73
0
10
0
0
0
0
10
0
10
0
0
% R
% Ser:
10
0
0
0
0
0
10
37
19
0
10
10
0
0
19
% S
% Thr:
55
10
0
0
0
19
0
19
0
0
0
0
0
19
10
% T
% Val:
0
10
0
0
0
0
0
10
0
0
19
10
19
0
10
% V
% Trp:
28
0
10
0
0
0
10
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
55
0
0
0
0
19
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _