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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
17.88
Human Site:
T575
Identified Species:
39.33
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
T575
C
P
Q
P
K
Q
L
T
T
D
G
L
P
Q
C
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
T574
C
P
Q
P
K
Q
L
T
T
D
G
L
P
Q
C
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
S501
G
D
P
G
P
L
F
S
A
I
V
L
D
Q
F
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
T575
C
P
Q
P
Q
Q
L
T
T
E
G
L
P
Q
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
T575
C
P
Q
P
Q
Q
L
T
N
M
T
Q
S
P
C
Chicken
Gallus gallus
XP_425053
1523
173782
T550
C
P
Q
P
Q
Q
L
T
A
Q
L
L
A
N
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
K446
N
P
K
L
K
D
T
K
L
L
K
E
L
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
N544
C
P
Q
P
M
Q
L
N
A
T
E
L
E
P
C
Honey Bee
Apis mellifera
XP_624355
1492
172466
N558
C
P
Q
P
Y
Q
L
N
S
T
M
L
E
P
C
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
N567
C
P
Q
P
F
Q
V
N
T
T
G
L
E
P
C
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
S691
E
G
E
N
R
T
I
S
E
N
D
M
E
N
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
100
13.3
N.A.
N.A.
N.A.
86.6
N.A.
53.3
60
N.A.
13.3
N.A.
53.3
53.3
60
6.6
P-Site Similarity:
100
100
20
N.A.
N.A.
N.A.
100
N.A.
60
66.6
N.A.
20
N.A.
53.3
60
66.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
28
0
0
0
10
10
0
% A
% Cys:
73
0
0
0
0
0
0
0
0
0
0
0
0
0
82
% C
% Asp:
0
10
0
0
0
10
0
0
0
19
10
0
10
0
10
% D
% Glu:
10
0
10
0
0
0
0
0
10
10
10
10
37
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
10
% F
% Gly:
10
10
0
10
0
0
0
0
0
0
37
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
10
0
28
0
0
10
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
10
0
10
64
0
10
10
10
73
10
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
10
10
0
0
0
% M
% Asn:
10
0
0
10
0
0
0
28
10
10
0
0
0
19
0
% N
% Pro:
0
82
10
73
10
0
0
0
0
0
0
0
28
37
0
% P
% Gln:
0
0
73
0
28
73
0
0
0
10
0
10
0
37
0
% Q
% Arg:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
19
10
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
10
46
37
28
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _