KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX1
All Species:
17.88
Human Site:
Y367
Identified Species:
35.76
UniProt:
Q9NRD9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD9
NP_787954.1
1551
177235
Y367
A
L
R
V
C
N
S
Y
W
S
R
E
H
P
S
Chimpanzee
Pan troglodytes
XP_001163196
1551
177072
Y367
A
L
R
V
C
N
S
Y
W
S
R
E
H
P
S
Rhesus Macaque
Macaca mulatta
XP_001111340
1551
176921
Y367
A
L
R
V
C
N
S
Y
W
S
R
E
H
P
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_001092767
1551
177113
Y367
A
L
R
V
C
N
S
Y
W
S
R
E
H
P
K
Rat
Rattus norvegicus
Q8CIY2
1551
177179
Y367
A
L
R
V
C
N
S
Y
W
S
R
E
N
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
F373
A
L
R
L
C
N
S
F
W
S
R
Q
N
P
N
Chicken
Gallus gallus
XP_425053
1523
173782
W354
M
R
L
C
N
S
Y
W
S
R
E
S
I
E
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
D210
P
D
P
S
S
G
P
D
S
G
S
Q
E
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
L337
M
G
Y
P
A
V
R
L
C
S
T
W
W
D
S
Honey Bee
Apis mellifera
XP_624355
1492
172466
N359
C
S
T
W
W
D
S
N
E
V
L
T
N
S
T
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
E347
R
K
R
G
N
K
C
E
F
R
T
E
V
G
G
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
S461
D
Q
D
E
F
S
E
S
Q
G
N
H
G
V
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.7
N.A.
N.A.
91
90.1
N.A.
73.9
65.1
N.A.
47.1
N.A.
39.9
40.3
34.3
41.6
Protein Similarity:
100
99.4
97.8
N.A.
N.A.
95
94.4
N.A.
84.4
78.4
N.A.
61.7
N.A.
58
60.2
55.9
59.3
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
86.6
N.A.
66.6
0
N.A.
0
N.A.
13.3
6.6
13.3
0
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
100
13.3
N.A.
6.6
N.A.
13.3
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
9
0
0
9
50
0
9
0
9
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
9
0
9
0
0
0
0
0
9
0
% D
% Glu:
0
0
0
9
0
0
9
9
9
0
9
50
9
9
0
% E
% Phe:
0
0
0
0
9
0
0
9
9
0
0
0
0
0
0
% F
% Gly:
0
9
0
9
0
9
0
0
0
17
0
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
34
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
17
% K
% Leu:
0
50
9
9
0
0
0
9
0
0
9
0
0
9
0
% L
% Met:
17
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
17
50
0
9
0
0
9
0
25
0
9
% N
% Pro:
9
0
9
9
0
0
9
0
0
0
0
0
0
50
0
% P
% Gln:
0
9
0
0
0
0
0
0
9
0
0
17
0
0
0
% Q
% Arg:
9
9
59
0
0
0
9
0
0
17
50
0
0
0
9
% R
% Ser:
0
9
0
9
9
17
59
9
17
59
9
9
0
9
34
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
17
9
0
0
9
% T
% Val:
0
0
0
42
0
9
0
0
0
9
0
0
9
9
0
% V
% Trp:
0
0
0
9
9
0
0
9
50
0
0
9
9
0
0
% W
% Tyr:
0
0
9
0
0
0
9
42
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _